32 with marked growth retardation (Nos. 3 and 5), T, levels before surgerv were lowerin subjects exposed in childhood than in unexposed controls. Subjects exposed as adults who developedeither benign or malignant thyroid lesions did not show notable impairment of thyroid function. The serum iodine levels of exposed and unexposed people for the past 15 years are given in Appendix 8. In 1965, the rates of urine and thyroid accumulation of 1321 were measured over a 4-hr period in 21 Rongelap subjects, of whom 9 were unexposed and 12 were exposed as adults.!8 The data are summarized in Table 26. Compared with North American normal values obtained in 196518 (urine, Agi #2; thyroid, Ag, 2=1; thyroid fraction = 0.33), both the exposed and unexposed Mar- shallese showed slow urine and thyroid transfer rates of extrathyroid iodide but a high thyroid fraction. Similar studies done in 1972 on ‘2? Rongelapese without detectable thyroid abnurmalities, Table 28 Thyroid Status of Exposed Rongelap Subjects Without Recognized Thyroid Lesions, 1974 Subject No. Age and sex (1974) 4M 58 6M 7M 9M 21 36 42 10M 44 Plasma Ty, ug/dl Pre-TSH 6.9 6.8 4.7 4.5 9.2 12F 16M 24F 38 39 33 6.5 6.4 8.2 35 M 37M 33 40 5.9 4.6 64 6.0 SIF 66 F 68 M 70 F 73M 76 M 78F 80 M S1F 82 M 83 M 85 M 1F 1iM 14 F 22 F 45 52 64 35 38 3t 37 66 28 70 20 20 74 70 45 37 6.9 7.0 8.9 7.9 7.8 3.4 6.3 8.1 3.8 53.8 6.2 78 5.1 6.8 6.7 35 44M 24 5.8 71F 48 4.2 34 F 39 F 41M 65 - 48 F 27M 58 F 63 F 67 F 32 M 47M Mean + S.D. 35 26 36 79 56 34 24 28 24 hr post-TSH Increment* 7.8 0.9 8.3 3.3 3.3 12.8 8.7 8.3 12.1 7.1 10.6 8.3 11.5 7.2 12.2 7.8 6.6 9.4 9.1 9.4 10.4 11.8 12.0 7.0 7.1 9.1 7.8 6.7 8.6 11.4 15 0.6 0.8 3.6 2.2 19 3.9 3.5 1.9 2.0 3.2 3.4 5.0 2.2 2.4 1.6 3.9 4.2 1.6 0.8 1.0 2.0 0.9 2.4 3.6 75 ug Ty dl 7.0 3.9 2.1 4.5 <1.0 18.5 9.1 4.4 5,3 4.4 144 3.1 2.6 16.7 21.7 4.4 18.4 6.3 5.1 3.2 39 3.1 6.0 1.5 2.3 4.7 8.8 3.0 3.4 3.8 78 2.3 L.4 3.9 3.0 27 18.6 25.5 212 4.2 5.3 6.3 2.7 10.3 75 8.4 *Normalin 13 Pittsburgh subjects: 4.7 1.0 pe/dl.38 pU/ml TBG- binding capacity, 2.7 8.2 8.2 7.4 6.64+1.7 Plasma TSH,** <1.0 7.0 2.352%1.2 **Measured in pre-TSH samples. Normal is <3 wl ml