32 Tabie 18 Correlation of Immunoelectrophoretic and Peripheral Blood Findings With Age and Radiation Exposure!} (D =decrease,; [ = increase) Unexposed group Exposed group Change Correlation Percentdif. Significance with age with age (r value) from unexposed (p value) Lymphocyte transformation BD 0.89 Serum proteins Total serum proteins Albumen I D I I Criterion Total globulins Alpha-! Alpha-2 Beta I A (IgA) I M (IgM) G (IgG) Kappalight chains. Lambda tight chains K/L ratio I I I I I D (IgD) Blood findings Hematocrit Sedimentation rate Total leukocytes Lymphocytes Neutrophils Platelets 0.68 35 245 — 15 + 15.0 2+ O1 37 43 —31.0 — 20.0 Ol 01 + 18.3 01 49 —17.0 05 .20 78 .96 24 41 — ~— — — + 74 22, 69 AS 4 —17.1 .32 I Immunoglobulins 11 38 I Gamma — 75 — 6.0 , — 3.0 O1 .03 I 20 D I D D I 47 72 43 91 44 + 2.9 +11.4 — 2.5 — 0.1 —13.8 07 08 39 1 .O+ D 65 — 84 .O4 4.0 8.0 3.0 14.0 0.4 98 Table 19 Serum Proteins, 1973-1974 Group Total protein Albumen Alpha |! Alpha 2 Beta Gamma Total globulin Rongelap Ailingnae Utirik Unexposed 7.760.70 7.99+0.51 7.60+0.50 7.60+0.71 4,.29+0.50 4.307+0.37 4.290+0.43 411+0.45 0.20+0.05 0.19+0.07 0.160.06 0.19+0.06 0.692-0.12 0.720.15 0.69 +-0.30 0.75+0.14 1.082-0.24 1.050.20 0.89+0.23 1.00+0.24 1.59*+0.41 1.76+0.38 1.67+0.45 1.57=-0.48 3.5420.58 3.600.356 3,330.50 3.52 0.54 podiploid levels were related also to radiation; this was more pronouncedin the males, with the exposed having 2.8 times as many hypodiploid cells as the unexposed, whereas the exposed femaies had 1.3 times as many as the unexposed. Polyploid levels were not found to be related to radiation. Both sex and chromosomesize appeared asfactors possibly related to hypodiploid levels. In all subjects, regardless of sex or exposure, the largest and most frequent loss of chromosomes was in the G(Y) group (2.3 times expectedloss). In the C(X) group, females lost 15.2% more chromosomes than expected and males 12.6% less. No sex or radiation effect was apparentin the otherfive chromosomegroups. A series of additional cultures indicated the presence of chromosomebreakage factor in the plasmaof the exposed subjects. In cultures of the latter, chromosome aberrations