®oh S PROSRSO REPRE 1 July 269 to 2d June 1970 407558 RESEARCH PROUDC? WP (11-1) 1784 & 2 Gulxaitted 30 June 1979 0 o TITLE OP VETTICATION < Rc A Stuay at wae VThysiolosicul Tuncticn ord Hilstoiesdfeat Changes an ‘Wryroids Trneshated with Padag.ctiv? Izdine a = = pao MRA DSPvon o 6 Brow Mi. Oclvna, M.D. , Bn. D. Professor of Surgery, Cause Western Heserve University eo INSTITUSION Cas? ‘ester feserve University School of Medicine at Cleveland htwpolitan General Hospital The investirations supported by this contract und dealing wv oh thefelizers ar 131] on the tiyreid continue ina variety of directicns and range froa g@linical research in ran tea variety ef experimental degimms in rats. Prinary qfforts =e directed toward study of the long term effects of the radiation on the physcoloisal function of thyroid cells, the nature of their survival, and the ultizvafe >ehavicr “ the cells with special attention tcward the develonmen. of nxiules meople sus « The ideas and experizental desirns have not only yrewn out of the long Jerm climcal neiniost or cur Cen patients (more than 20 years), but from participatfen by the perp investigater (along with others) in several other majer projeqts Zealis with 1 effects. These are: the Steering Committee for analysis amd study of 38 ,090 fatients in theCocperative Thyrotoxicosis Therapy Foll 1.) Chairman of 2.) Participant (vith Or. Robert A. Conare, Brookhaven ! haven National in the surveys cf the Marshallese natives exposed to radioiodi the first thermonuclear explosicn 3.) Participant in the surveys of goiter in children yin the @ UtahJal 1 ~ oe. J fallout (1934) erea and in special studies performed on individuals in that population. LEGAL NOTICE Tide Pegrt ens SEER os Oh coemmne of emnent epmenered ourt, Eerie Gs tamed Gaam, cor Ge Comeneenen, eat wee prewey creme oy teled of Ge Commence B, Asmat ety SeRMns SAD foeumet w Ge wee of, or tee deme ree en Oe aon af Gap eerie, CERRGTiAR. eeeeed, oe eee Garteged ty eee eget Ao mad © ie sien, Tene oS ae eed of Ge Conrmeneee mertee oe om Mee oe eee selecta BEST COPY AVAILABLE