thyroid suppression. With regard to the second criticism, i.e., that if a cumulative acquisition of internally deposited fall-out debris from a series of shots is extrapolated back to the date of the initial shot, a larger than calculated dose will result; this may in part explain the extremely high 14odine-131 value as extrapolated back 82 days to the first shot of the CASTLE series. Despite the fact that the subsequent shots were in one case only 130 KT and in the remaining four cases were water surface bursts, it is felt that the fraction of iodine-l31, especially from the 13 MI YANKEE event 14 days before the urine study, considerably influenced the results. If as Figure 22 indicates, the body burden on the 82nd day is a cumulative function of all preceeding shots, then the calculated body burden for the first day is approximately 400 times too high. Thus 6.4 x 10" 4.0 x 10 = 1.6 x 10° microcuries for the actual burden on the first day is considerably more within reason. If 1t is assumed that iodine-131 is taken up biologically in comparable amounts regardless of proximity to the area of detonation, and that iodine and strontium alike accumulate in the body over a period of time from a series of shots rather than as a single acute dose, then support for these assumptions can be found in the CASTLE experience as well as in reasonable compatibility with subsequent experimental data. CQ. \VV Deleted . 126