SUMMARY SHEET Committee on Radiction Studics(MAIL BALLOT) — Ca2185 Februcry 1954 Council Mecting es WWlidien H, Baucr y M.D.y Professor of Pathology, Director of-theDepartrient’ of Pathology: . Arthur 4, Burke, Jr., Beas, Meds, Graducte Student, —‘Research fellow, St, Louis University, School of Dentistry, St,: Louis 34.Missouri’ "The x-rey sensitivity of ascites tumor in vitro. under oxyecn and nitrogen at room and low temperature" Year ist Requested | $9,960 Regormended oo ote REQUESTED BEGINNING DATE: RECOMMENDATION : PRIORITY SCORE: Grant. Poriod July 1, 1954 Approval . i ~ 8 Disepproval = 3 300 (based on 6 ratings) COMMENTS s approval The problen submitted appears to be c continuation of the work initiated by Mr, Burke, in association with others, at the Ovk Ridge laboretorics, There is nothing novel or fundamental in the epproach proposed, though the experience in the Biophysics Departnent of this institution in preserving living cells in the frozen state (-190°C), and the experience with ascites tunor suggests that the proposed study of the radio sensitivity of an ascites tumor in vitro would be well carried out, Although no najor contribution is to be expected, and the results of this investigation can be predicted from the many data already available in the literature, it seems worthmwhile to support this project, The sum requested appears excessive; it is difficult to justify the sclories for both a full-time technician and an animal coretaker, The research fellow and part-time animal attendant should be quite adequate to cerry out the work planned, Therefore, approval at the level of $4,500 ~ $5,000 is recommended, (over) RINALACTION? Februcry 1954 4:prowals “6,240 rlus owertiead or '6,799 for one year = &/1/5h @ 5/31/'556