“a
1034

NUCLEAR SCIENCE ABSTRACTS

Vol. 19, No. 6

ated the conversion of MIT to DIT as well as coupling of

appeare that some I.C.R.P. recommendations for maximum
permissible body burden must be revised. (auth)

cation of the #1 concentrated by the oxplant, which was
reflected mainiy in its increased incorporation into Ty.
However, increased !'1 utilization in thyroid glanda of 17—-

0787
EXPERIMENTAL UPTAKE OF STRONTIUM-85
BY FRESH-WATER ORGANISMS. W.A. Brungs (Robert A.
Taft Sanitary Engineering Center, Cincinnati). Health

DIT, ard thus formation of thyroid hormones. Addition of
TSH to the serum-containing medium {mproved organifi-

17,5-day-old embryonic rate cannot be ascribed to TSH

because the serum was prepared from the blood of rats
that hed been hypophysectomized 6 monthe previously.
(auth)

and potassium on the uptake of dissolved strontium-65 by

a7se
Q1}-UPTAKE IN CERVICAL MUCUS DURING
THE MENSTRUAL CYCLE, Hilda EB. Parialer, Alberto B.
Houssay, Ana C. Zapeta, Adela C, Valerga, and Jorge F.
Cordero Funea (Centro de Endocrinologia, Buenos Airee).

Fertility Sterility, 15; 433-9(Aug. 1964).

The glands of the uterine cervix concentrate 11 and it

appears fn the cervical mucus in high concentrations,
Since cervical mucus undergoes cyclic changea during the

human menstrual cycle, a compariaon wag made of !?!I uptake by the cervical mucua during the estrogenic and progestational phases of the sexual cycle in normal women,

women, The first 320 performed between the I2th ant
14th days of the cycle (firat phase) and the eecond hetween
the 25th and 27th days (second phase), by injecting intravenovaly 100 ¢C 'E, Peripheral blood and cervical mucus
were obtained at different intervals 20 to 135 min after the
injection. The ratio, mg cervical mucua: yl plasma, called
the mucus/plaema ratio 1M,P) was calculated for every
sample. Curves were obtained by plotting the M,P ratios,
the €9-min sample being chosen to represent 1007 valve in
each indtvidual curve, The curve representing the first
phase of the cycle Increased rapidly during the two hr of
the experiment, the 120-min value being 50% greater than
the 60-min, The higheet value lu the second-phase curve

was obtained after 60 min, it decreased slowly thereafter,
Thus "1] uptake was greater in the progestational phase.

This difference coincides with the change of other characteriatica of the cervical mucus such ag viscosity, osmotic
pressure, transparency, rate of secretion, and chemical

composition, To find out If the cervical glands are able to
concentrate other ions, these experiments were repeated,
using ?Na, 19 three normal women, but Na uptake by the
cervical mucus could not be demonstrated. (BBB)

S755
ON THE RETENTION OF CESIUM-137 IN PEOPLE. M. A. Van Dilla (Loe Alamoe Scientific Lab , N.
Mex.). Health Phys., 11: 21-2Q@an. 1968).
Cestum-£37 retention following four cases of accidental
contamination was measured ag a function of time in the
Los Alamos human spectrometer and counter. Inhalation
waa the primary route in at least three of these exposures.
A simple exponential function fite the data well, the biologi-

cal half time averaging 128 daye. Guth)

FATE OF THE IODINE RADIOISOTOPES IN THE

Boulenger (CEN, Mol, Belg.). Health Phys., 11: 23-35

Qan, 1965).
Fate of the iodine Isotopes and resulting organ exposures
were studied using a four-compartment model previously
proposed to account for the metabolism of this element.
Mathematical equations were established for this model

from biclogical data accepted in the human. They were used

to calculate the amounts of iodine i231 in the thyroid and in
the remaintng bod) as a function of time in case of a single
or a chronic contrminatton; in the Intter case three phases
were coraliored: rise, equilibrium, and decreaze after removal of the contaminatirg eoutce. The importance of the

G ity stable iodine intake fram the food was emphasized.

Sse of the theoretical retulte,werg checked by expertrece cgersht , dusters, Caleutstions were exter? Ji>
bie
the ding dg
op
TA or to determing the es.°
®

'

noe

they

-

-

strontium-86 int

mie macrochirue. The distribution of

ced

to a

containing macrofeuna

indigenous to the Midwest was algo investigated. Of the four

cations tested, only calctum wag found to have a elgnificant

effect within the experimental range on the uptake of
atrontium-66 by smal! bluegille, Date from the pod aptake
study indicate that after the 80-day experimental period
only 25% of the atrontium-85 remained In the dissolved
phase. The total calculated activity in the experimental

fauna never exceeded 0.9% of the smount added, The remaining radioactivity was aagociated with the substrate.
related to age of the test organiems. (auth)
a7Ee

ABSORPTION OF STRONTIUM-90 IN MAN.

Minoru Fujita Gapan Atomic Energy Research Inst.. Tokyo}.
Health Phys., 12: 47-80Qan. 1968).

Analyses were performed with reference to the levels of
“Sr and stable calcium tn diet and excreta of man. From

the data obtained, the abeorption of Sr was estimated. Four
healthy volunteers received the same diet for 7 periods,

each period consisting of five consecutive days, but, except
for the periods examined the subjects consumed any food

they liked. The given diet contained nearly 0.56 g of Ca per

day. The daily intake of "Sr ranged between 7 and 13 yyuC
according to the faliout levels in the diets. The absorjtion

coefficient, f,, per §-day period of the four volunteers aver-

aged about 0.38 with a large fluctuation of from 0.09 to 0.63.
However, values of f; over a considerable Ume around two
periods ranged between 6.20 and 0,32, making a strong con-

traat with the range between 0.09 and 0.48 obtained for the
same §-day period. (P.C.H.)

sree
FUNDAMENTAL STUDIES ON THE CONTAMINATION OF MILK BY RADIOACTIVE STRONTIUM SPECIALLY, ON THE MECHANISM OF CONTAMINATION,
Akira Yuyama, Iwate Daigaku Nogakubu Hokoku, 6: 49-80
(1962), Gn Japanese)

The
hantem
of milk
by radi
ontium
wae investigated by administering “Ca and "Sr to iactating
goate. Metabolism changes tn these animals were also ob-

served. Experimental methods aad results are discussed.
WJ RD.)

8769

CHEMICAL MECHANIOMB UNDERLYING THE

BIOLOGICAL MECHANISMS OF THE AGING PROCESS.

HUMAN AND ESTIMATION OF THE RADIATION EXPOSURE. J. F. Colard, W.G. Verty. J. A. Henry. and R. R.

foc?

amail bluegilis,

The data also indicate that strostium-85 accumulation is

Two ""] studies were made at 2-month intervals in 12

~—~)8786

Phya., If: 41-6Uan. 1968).
Factorial studies were conducted to determine the effects
of variable concentrations of calelum, magnesium, sodium,

tk

me

fas

n-

i

Johan Bjorksten and Fred Andrews (Bjorksten Research

Foundation, Madison, Wie.}, J, Am. Gertat. Soc., 12- 627~

3) uly 1964).

New data related to the chemical mechanism underlying
the blologica]l mechaniam of somatic mutation ag a factor

in aging are discussed. It le noted that cell cross -linkage
is the initial step in aging and ultimate deatruction of the
cell. (J.R.D.)
aver

PLACENTAL TRANSFER OF F'" IN SHEEP,

James W. Bawden, A. Sark Wolkoff, and Charles FE.
Flowers, Jr. (Univ. of North Carolina, Chapel Hil),
Dental Res., 43: 678-83 Sert.-Ort, 1964).

J.

A surgical techaique was employed on eight pregnant
ewes to gain access to the maternal and fetal circulations

with the lamb ie utero. Injections of @F (f mC) were made
into the animalg ia order to atady various aspects of
maternal-fetal "F exchange, The data revealed that mat 7 al piisma clearance of 'F Le quite rapid and that feral

patua levels are relatively low when compared to materocl leva.e, Uptake in fetal dental anc skeletal thames was

e
’

oa. Fetal incisor teeth yielded from 800 to 166s rn~
Coord Sere esoniva cot et OR tn

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