Table 20
Growth and Thyroid Studies in Subjects With Thyroid Abnormalities
-
Neck |]
Growth
Subject
No.
and sex
Thyroid
abnormality
Skeletal
ranking,
ye
at 4 hr,"
Statural
ranking,”
percentile
Year
tested
Chronological
age, yr
1965
13
3
<t0
,
% of dose
Serum iodine,
ugh
Post
TSH
Pre
TSH
T,I
PBI
3.
M_—
Atrophy
9
M_—
Atrophy
1965
1966
13
5%
<0
17
F
Nodular
1965
[5
13%2
90
6.8(°64)
21
F
Nodular
goiter
1965
1966"
15
15
10-25
9
F
Nodular
19654
i6
16
2
M_
Nodular
goiter
1965
1966"
13
11¥2
25-50
20
M_
Nodular
1965
19
Adult
25-50
72
=F
Nodular
1965
18
17%2
>90
42
F
Nodular
1965
15
13%2
10
61
F
Nodular
1965
20
Adult
50-75
54
M_
Nodular
1965
13
13
90
19 M_ Nodular
1965
17
15%:
10:
75
goiter
goiter
goiter
goiter
goiter
goiter
goiter
goiter
1966
1966"
1966°
1966
1966
1966
1966"
>90
36 M_
Nodular
1965
19
18
33°
Nodular
1965
13
13%.
>90
id F
Nodular
1965
goiter 5" 4466
13
10%
<10
59°F
Solitary
35
64
F
Carcinoma 4965
3966"
31
40
M_—
Solitary
40
F
goiter
goiter
1966
1966
£965
nodule “"" 1966
nodule
1965
1.4
0.8
> 120
1.9
3.1
0.8
1.8
149
248
1.8
<0.5
372
8.1('64)
1.3
<0.5
440
125
1.0
3.2
8
7.1
6.5
18
5.7
1.7
(29)
(23)
7.9
5.2
4.2
2.6
(31)
(3L)
6.5
4.2
a3 -
(15)
12(10)
19
"
(24)"
.
(24)
.
5.7
4.6
-§7.9
4.9
.
5.0
(24)
17 (9)
(14)
7°(20)
(38)
(19)
(28)
<17
<3
<17
$3
<17
4.3
<1?
5.9
3.8
197
8.2
5.3
«8.6
4.9
3.4
2.0
3.9
¥£
*
4.2
_
9.6
26.6
430
4.1
(16)
159
-
8.3
~
Serum
TSH,
ng.’ml
7.0
4.9
3
21
19
8.6
10.3°°
7.3
6.6
23.5
4.8
,
-
“Nalues in parentheses obtained at BNL.
"Relauve statural growth expressed as percenule ranking compared with growth curves of unexposed Marshallese
children.
Assays in 19635 could not detect levels below 3 nanograms/ml. Seven unexposed children in the same age group had
<3 ng mi. Assays in 1966 could not detect levels below 17 ng/mi. Three exposed children without thyroid disease
Nos 6,8. and 32) had < 17 ag’ml. Two children exposed i utero ‘Nos. 84 and 86) and two unexposed children hac
1) ng mi. The 1966 levels were obtained about 3 wecks after cessation of thyroxine therapy. the 1965 levels. before
therapy was instituted. We are grateful to Dr. William Odell at the Naconal Institutes of Health for carrving out these
abSSANS.
“Post partial thyroidectomy
“While taking thyroxine.