29 The depressed thyroidal iodine uptake rate and renal excretion rate are puzzling, and no explanation for them !s available at this time. Developmentof Thyroid Abnormalities During the past 3 years, beginning at 9 years after exposure, a total of 18 cases of abnormalities of the thyroid gland have been detected. Nodules of the thyroid gland were found in 16 cases, and 2 cas: z have hypothyroidism with no nodules. All occurred in the more heavily exposed Rongelap people except for one woman in the less exposed (Ailingnae) group. A thyroid nodule was first noted in 1963 in a 12-year-old girl in the exposed group, and in 1964 two additional cases with nodules were found in exposed girls 13 and 14 years of age.’”*? In March 1965 three additional cases in exposed people were noted in boys Table !7 Thyroid Abnormalities in Exposed Rongelap People, 1966 Subject No. and sex Present age, yr Age at exposure, yr Year Age, yr Findings 3° M 13 I 1965 12 5 M 13 1 1965 12 17 F 21 =F 5 15 3 3 1963-12 1964 33 Adenomatousgoiter; total thyroidectomy, 1964. No recurrence. 69 F 2M 20 M 64 F 16 13 19 42 4 1 7 30 196414 1965-12 1965 18 196541 Adenomatousgoiter, partial thyruidectomy, 1964. No recurrence. Hypothyroid, PBI <2 hg% March 1965; retardation of growth preceded these findings Ly a numberof years. 3/66 growth spurt and improved appearanceon thyroxine. Hypothyroid, PBI <2 we% March 1965; retardation of growth preceded these findings by a numberofyears. 3/66 growth spurt and improved appearance on thyroxine. Adenomatous goiter; tatal thyroidectomy, parathyroidecton:y, 1964. No recurrence. Adenomatousgoiter, partial thyroidectomy, i965. No recurrence. Adenomatous gin er, partial thyroidectomy, 1965. No recurrence. Mixed papillary and follicular carcinoma,total thyroidectomy- surgical and therapeutic radioivuine, 1965. No recurrence, 72 42 18 15 6 3 1965 1965 «17 14 Three-mm noduleleft Icbe. 9/66 nodule not palpable. Two-mm nodule right lower lobe. 3/66 nodular enlargement (~1% X normal) entire gland; firm 5-mm nodule right lobe. 7/66 subtotal thyroidectomy: adenomatous goiter. él F 20 8 1965 19 40 M 4] 29 1965 40 59° F 46 94 54M 13 1 1966 13 5 1966 «17 7 1966 19 IS M 36 M 19 196545 Six to 8-mm smooth nodule left lower pole. 3/66 1-cm nodule left lobe. 7/66 subtotal thyroidectomy: adenomatousgoiter. Two-mm nodule right lower pole. 3,/66 no nodules detected. Five-mm nodule midline. 3/66 same. 7/66 ¥: btotal thyroidectomy: adenomatousgoiter. Nodular enlargement (~1% XX normal) left lobe and isthmus with 2-mm firm nodule. Multinodular soft enlargement entire gland (~1!'2 x normal). 1cm nodule right lower pote. Slight nodular enlargement, entire gland. 1-cm nodule, not ciearly demarcated, at right lower pole. Many tiny nodules over surface of gland. 43 F 13 1966 13 9.63 questionable irregular gland. 3/66 definite 5-mm nodule left lobe. 7.66 subtotal thyroidectomy: adenomatous goiter. Hurthle cell adenoma. 65 OF 13 i 19663 9/65 questionable small nodule. 3.66 5-mmnodule right tobe 7/66 right subtotal thyroidectomy: adenomatous goiter. *Exposed to only 69 rads whole-bodyradiation and presumably proportionate! y less thyroid dose.