' sbie . teow ot co c . e Sie an no to Sat Siig Dawe te tee he ka Errors in Human Hemoglobin as a Function of Age 2i3 Table I. Substitution frequency of isoleucine for other amino acids in human hemoglobin from 25 Marshall Island people and 3 ORNL laboratory personnel Sample Exposure Ageat exposure Ageat Sex present Substitution Average + frequency (x 10-5) SEM (x 10-5) years NTS 15 months 21 175 30 years 24R 33R 35R 42R WIR 175 175 175 175 175 l3 years 1 year }2 years 2years 27 years 6A 69 44Q 8669 1gsR 8A. 45A SIA 813U 815 829U 836 839 B41U 846 867U B68U 944U 1547 1549 EB WL RAP 8360 8368 867Ua 867UB $68Ua 868UB 175 24 years M_ 50 M 33 21 32 22 47 F F F F F 44 F 3.58 5.06 21 3years 23 Tyears 27 F 0 0 0 0 0 0 0. 0 0 20 24 35 41 46 41 51 46 51. M M F M F F F F F 3.37 2.57 3.47 2.45 1.89 3.56 2.41 2.12 4.35 0 60 F 7.15 34 M 17 months 69 31 years «69 0 0 0 0 0 21 51 49 21 45 43 6.98 F 12.93 F 3.65 M M M M M ‘ 13.45 4.74 5.19 10.40 8.29 1 year 69 M ,19.79 4.04 i 8.81 £1.96 ) _-5.941,92 2.12 “ oo 3.20% 1.52 | 3.93 1.57 2.84 4.37 3.36 | 43.5240.45 | ‘ Soy a . we a . ; . s, OS ws So 2.05 4.41 1.99 3.40 1.76 5.04 m + 3R 10R