we

2,500;

2

a
°

e

ee

®

e
3 1,500:
e

e
3
°

e

e

} 1,900
2

e

°

e
e

e

500

e
e
Dese of ist Day

70
L

100
Dese during 2 Weeks

Fig. 3.

130

190

250

200

300

400

i

L

e
e

s

310

370

40

R

500

600

700

R

1

1

1

Correlation between Minimal Neutrophils Count and Dose of Gamma Radiation

stage in severe cases, which showed remaining

and proliferation of plasma cells and reticulum

critical stoge

cells.

With the beginning of recovery, aplastic

marrow changed to hypoplastic and then turned

into a type of maturation arrest. Recovery was
not complete even after one year. In the cases
not so severe as these, the bone marrow was

&

Cumulotive Persent

100

not aplastic but hypoplastic or a type of maturation arrest even at the critical stage.
1 ano

i

1

rn

$

x 10-64

RBC

Fig. 4.

Cumulative Distribution Curves (RBC)

Platelets
Platelets counts showed increasing depression,
reaching minimum at the 4th-7th weeks. The
recovery began during the following several
weeks. The cumulative percentage curve still
displaced to the left of normal curve after one

yeur.

The results of other tests related to haemorrhaze showed depression at the early stage in
general and recovered by the 10th week.
Bone marrow
The bone marrow was aplastic at the critical

Morphological abnormalities
Several morphological abnormalities, e.g. abnormal granules in lymphocytes or neutrophils,
vacuoles in various leucocytes and megakaryocytes, giant nuclei and hyper-segmentation of
neutrophils, binucleated lymphocytes, abnormal
mitosis of erythroblasts, etc. were observed for

about one year, especially at the critical and
the recovering stages.
Erythrocyte sedimentation rate was accelerated in
the early stage in some Cases.
4. Spermatopoiesis
The examinations of spermatopoiesis were performed on 18 patients several times.
Number of spermatozoa decreased about 2
months after the initial exposure, and azoo-

Select target paragraph3