Birth Rate and Generation Time For most purposes, United States, it , a generation is taken to be 30 years. is In the currently a bit shorter, but 30 years is still taken as a convenient simplification. For the Marshall Islands, the Five Year Comprehensive Health Plan gives a breakdown by age of mother (Table V-3, page 120) that shows the age of mothers at the “average” or "middle" birth to be only 23-24 years. However, no information is available on the age of fathers, who seem likely to be older than the mothers, and in any case the usual 30 year interval is used here. It should be noted that to the extent the Enewetak generation is actually shorter, this tends to overestimate dose to the parents of the average child, and thus the genetic health risk estimates. While genetic risk estimates may be expressed per live birth, thus avoiding any assumptions about future birth rates, it is helpful’ to attempt to estimate the total risk for the entire next generation of the Enewetak people. As a minimum, we might simply assume a ‘“‘replacement" birthrate of 453 live births over the next 30 years, or about 15 births per year. AS amaximunm, we might assume that the average birth rate in the entire Marshall Islands for the 20 years from 1955 to 1975 might apply to the Enewetak population for the next 30 years. From Table III-1 of the final draft of the Marshall Islands 5-year Health plan, one can calculate that the average yearly birth rate for the period (it seems remarkably stable over this period) is 39.7+ 4 births per 1,000 of population; for practical purposes 40 per 1000 or about 11 per year for the 273 people assumed to return to Enewetak and about 7 per year for the 180 people assumed to return to Enjebi. Of course, should the present birth rate and current population growth rate of the order of 3-4% per year continue, the absolute numbers of births will grow during the coming 30 years. Assuming a 4% growth rate, the Enewetak population may include 816 people 15 years from now, and about 33 births might be expected that year, while in thirty years there would be almost 1,500 persons, with well over 60 births per year. It seems unlikely that the population will grow to this extent; in view of the uncertainties involved, perhaps a reasonable assumption would be that there will be not more than roughly 1000 births in the population during the next 30 years. With exponential population growth, roughtly one-half of the births expected over 30 years will occur during the first 20 years; the remainder will occur during the final 10 years. In view of the uncertainties involved, it seems reasonable to assume as an upper credible limit that there will be 1000 births, the average accumulated parental dose for which will be that accumulated for the first twenty years. However, the doses were calculated for 50 years, and since these are not enormously larger than the 20 year integral doses (see Fig.3 of Dose Assessment), they are used here as upper bound estimates of the doses of genetic significance in calculating genetic risk.

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