unknown cause. There was no diabetes, and his creatinine. Nevertheless, she was started on urinary sediment showed red cells, casts and protein. The serum creatinine was 3.4 mg/dl. He had chronic venous insufficiency in the legs and a left hydrocele. A serologic test for filaria was negative. There was also a mild macrocytosis; a serum B12 level was low normal. The cause of death is not knowa. intramuscular B12. Mammography was normal and Subject No. 6. This 69-year-old man died on Ebeye in 1989. His medical problems in March 1988 included diabetes (status post leg Ebeye in 1990. He had advanced diabetes mellitus with nephropathy, retinopathy, and neuropathy. Whenlast seen in March 1990 his creatinine was 12.4 mg/dl and the hemoglobin level was 10.4 g/dl. A HbAic level was 6.8%, only slightly elevated. Flexible sigmoidoscopy was negative in 1987, and a chest x-ray at that time showed noactive disease. He was being followed by the Diabetic Clinic on Ebeye. His deathcertificate listed renal failure due to diabetic nephropathy as the cause of death. amputation) with chronic renal failure, severe neuropathy, and eye infection from recent cataract extraction, for which he was referred. He was moderately anemic with a Hb of 9.6 g/dl. The cause of death is unknown. Subject No. 7. This 42-year-old man died on Majuro in 1989. He had diabetes, extremely carious teeth, a cataract, and a disabling arthrogryposis. When last seen in 1989 his only medication was glyburide. His blood count and serum creatinine were normal. Hewas referred for cataract surgery. The death certificate lists overwhelming sepsis and severe pneumonia as the cause of death. Subject No. 8. This 89-year-old woman died on Ebeye in 1990. No important medical problems were noted when patient was last seen in March 1988. She had severe kyphosis, cataracts, and perhaps a mild dementia, but in general annual examinations indicate she was usually in quite good health. Her blood count was normal and a Papanicolaou smear was Class I in 1988. Medications included only acetaminophen and a skin antifungal agent. The cause of deathis unknown, Subject No. 9. This 76-year-old woman died on Ebeye on December 31, 1987. The death certificate diagnoses were cardiac failure and bronchitis. At the time of her last complete medical examination by the Brookhaven team she had a moderately severe anemia (hemoglobin level: 8.8 g/dl) and recent weight loss. The mean corpuscular volume was 98 fl. and there was some hypersegmentation. A serum B12 level was somewhat low (170 pg/ml), but the urine methylmalonic acid level was normal at 0.8 ug/mg her Papanicolaou smear was class I. When seen several months later in follow-up, she felt well. A flexible sigmoidoscopy was normal. It may be relevant that her husband had died recently, andit is possible that he had advanced tuberculosis. Subject No. 10. This 59-year-old man died on Subject No. 11. This 61-year-old man, a former heavy smoker, died on Majuro in 1989. He was known to have chronic renal insufficiency thought to be due to diabetes. He was referred in 1987 for evaluation of this problem. An_ ultrasound examination by the Brookhaven team revealed no calculi or hydronephrosis; renal size appeared normal. He had gout, and the renal disease could have represented uric acid nephropathy. There was a suggestion of pleural effusions on chest x-ray in 1988 when he was referred for further evaluation. Whennext seen by the medical team in March 1989 he had lost much weight and a hilar mass was noted on chest x-ray. He was referred for evaluation. Carcinomaof the lung was indicated on his death certificate. Subject No. 12. This 73-year-old woman had breast cancer diagnosed in 1985 after a breast nodule was detected during het annual medical program physical examination. A mastectomy was done that year. She died in 1991. Whenlast seen by the medical team (March 1989) there was no evidence of metastatic disease, and the cause of death is unknown. Subject No. 13. This 64-year-old woman died on Ebeye in 1988. Her last complete Brookhaven examination was in 1986, when her problems included insulin-dependentdiabetes mellitus, urinary tract infection, and abnormal liver function tests. When repeated, the latter showed only a minimally