- 56 - AAI 4 s o3 4 “ tL Ww 4 & 23 4 oe (Or 3 <u} 4 = a_i -| T L + uw re 1 PANEL A q r Ww >E <x if - ~ <= L oi I wv ™ LW of “) zr: wm 4 4 4 f S2 = ie 1Ok- <x OF 4 4 4 1 Lo BC F, o9 ' 7 r) a - ; r 4 4 ew 4 <t Ww is J . a be 4 L 800 _ | 1000 | 1200 AGE (DAYS) The logarithm of the age-specific mortality rate (Gompertz transform) for all causes of death except leukaemia in BCF1 mice of both sexes trradtated in duratton-of-life experiments at the exposure rates shown. Straight lines were fitted by least squares through the control tnetdence at 100 days of age when the exposure began. 000 I>. Tr T P.100 BOF, of*Q 800 71 ~jQ080 600 40.060 ~ a ~~ | 1 | > z a < | | 1 > ra > PANEL B > a uu J w a Ww 4a0c20 200 a Ww . if << Fea < \ = <x observed—\‘e predicted Lu ye \ = s 100 “2010 80. ~0.008 4 tL i SON gS 12243243 3 « > ! 56 006 DOSE C(R/DAY) Plots of the Mean After Survival (MAS, open circles) and of the slope of the Gompertz transform (closed ctreles) versus exposure level. Data are for BCFI mice of both sexes, as in panel A. The dashed line is that predieted by MAS from the estimated Gompertz slopes relationships. Figure VII. tn order to show the consistency of the The lines were fitted by least squares analysts. (Data in panels A and B are from Sacher, Grahn, Fry et al. [S85]