of the same age. Thus, to the precision obtainable with such a small sample size, only the radium-related tumours contributed significantly to life-shortening of this population, with no evidence of non-specific effects. C. 359. DATA FROM RADIOTHERAPY PATIENTS Doses administered to patients surviving radiotherapy are rather well known and may be taken as the independent variable against which any possible life-shortening could be tested. The limitations with this group of people are due to partial-body exposure and to the possible effects of the disease initially requiring radiotherapy. 360. The relevant data should thus be taken critically. Studies reported on patients are few and all of them negative, in that none show life-shortening attributable to radiotherapy. S¢rensen [S40] studied patients treated for cancer of the uterine cervix in 1922-1929 in Copenhagen, surviving for at least 5 years after treatment and having been followed for the 20 years thereafter, ments: Out of 798 eligible patients, 184 met the above require- they were 49.1 years old at the time of treatment and the average radium treatment received was about 6500 mg-hours, equivalent to 4.4 Mgm rad. Sgrensen found that survival was not correlated with the stage of the disease at diagnosis. Each patient lost on average 3.5 years of life by comparison with the mortality experience of female Danish population. This excess of deaths was exactly accounted for by patients who died during observation time for a recurrence of the neoplasia and there was no evidence that irradiation per sehad decreased the survival rate of the patients without recurrence. 361, Newell [N11] attempted to establish some correlation between integral radiation dose and longevity in 217 women treated by radiotherapy at Stanford University in 1924-1947. The patients affected by cervical carcinoma in stages I and II had survived fro 10 or more years after treatment. Radium treatment alone (6 Mgm rad) or radium in conjunction with x rays (37 Mgm rad) were used in the therapy. From the data Newell concluded that no life-shortening attri- butable to radiation had occurred in the patients. ted independently by Kohn, Bailar and Zippin ginal records: their conclusion was the same. The data were also evalua-— [K20] who had access to the ori-