Table 18 Correlation of Immunoelectrophoretic and Peripheral Blood Findings With Age and Radiation Exposure!3 | D = decrease; I =increase} Unexposed group Exposed group Change Correlation Percentdif. Significance Criterion with age with age (r value) from unexposed ( p value) Lymphocyte transformation D 0.89 -— tl 0.68 Serum proteins Total serum proteins I .35 -— 15 2+ Albumen D 45 + 15.0 01 Tota] globulins Alpha-1 I I 38 37 -17.1 —31.0 ol Ol [ [ 32 75 - 60 — 18.3 Alpha-2 Beta Gamma Immunoglobulins A D M G (IgA) tIgD) (IgM) (IgG) Kappalight chains Lambdalight chains K/L ratio Blood findings I 4B — 20.0 01 .03 OL I I I [ 49 .20 20 78 -17.0 — 3.0 — 40 — 80 05 98 74 22. I Al + 04 a4 I I 96 24 — 3.0 — 14.0 69 15 Hematocrit D 57 + 29 07 Total leukocytes Lymphocvtes Neutrophils Platelets D D I D 45 91 44 65 — — — 39 31 0+ O04 Sedimentation rate I 72 +11.4 25 0.1 13.8 84 08 Table 19 Serum Proteins, 1973-1974 Group Rongelap Ailingnae Utirik Unexposed Total protein 7.760.70 7.99051 7,600.50 — 7.60%0.71 Albumen Alpha 1 Alpha 2 Beta Gamma Total globulin 4.224050 4.30+0.37 4.294043 4.1140.45 0.2020.05 0.19+0.07 0.16+0.06 0.190.06 0.69+0.12 0.72+0.15 0.69%0.30 0.750.14 1.082%0.24 1.05%0.20 0,890.23 1.00%0.24 1.59+0.41 1.76+0.38 1.670.45 1.5720.48 3 54270 58 3.60 = 0.56 3.330.350 3.520.354 podiploid levels were related also to radiation; this was more pronounced in the males, with the exposed having 2.8 times as many hypodiploid cells as the unexposed, whereas the exposed females had 1.3 times as many as the unexposed. Polyploid levels were not found to be related to radiation. Both sex and chromosomesize appeared asfactors possibly related to hypodiploid levels. In all subjects, regardless of sex or exposure, the largest and most frequent loss of chromosomes was in the G(Y) group (2.3 times expected loss). In the C(X) group, females lost 15.2% more chromosomes than expected and males 12.6% less. No sex or radiation effect was apparentin the otherfive chromosome groups. A series of additionalcultures indicated the presence of chromosome breakage factorin the plasmaofthe exposed subjects. In cultures of the latter, chromosome aberrations