4
lated directly to radiation effects during thefirst

few years post exposure. No prophylactic or specific therapy for radiation effects was ever con-

sidered necessary or given. Epidemics of chicken
pox and measles that occurred during the first
year showed nogreaterincidenceor severity in the
exposed than in the unexposed Marshalles people.
Duringthefirst months post exposure about %
of the exposed people exhibited loss ofweight of several pounds. This may possibly have been related

to their radiation exposure, although it was difficult to rule out possible effects due to change of
environment.
At 3 years post exposure the immune response to
primary and secondary tetanus antitoxin was

tested and found notto be significantly different in
the exposed compared with the unexposed populations.

There were 10 deaths in the exposed popula-

tions over the 10-year period (see Table 6). Of
these, 2 deaths were recorded as due to malignan-

cies. The 10 deaths that have occurred in the ex-

posed population represent a mortality rate of 12.2

per 1000 population per annum, compared with

8.3 for the Marshall Islands as a whole (1960).

The somewhat higherdeath rate in the exposed
group is partly offset by the higher proportion of
older people; those >65 years of age were originally 20% in the exposed group and only 7% in the
unexposed group.

Growth and development studies on the children

(height, weight, anthropometric measurements,
and radiographic studies for bone age) havere-

vealed slight retardation in growth and develop-

ment in the boys exposed on Rongelap who were

<12 years of age at the time of exposure, particu-

larly those 12 to 18 months of age at exposure.
Only slight immaturity was noted in the female
_a

children of this group. In studies of children born

of exposed parent(s), it was noted that males

showed a slight growth retardation andslightly
lower levels of peripheral blood elements compared with male children of unexposed parents;
however, this latter finding has not been evident

since 1963. Theslight growth difference does not
appearto justify a conclusion that thereis an association with exposureof the parent.

It was difficult to evaluate the effects on fertility.
However, a review of the birth rate of the exposed

groupsoverthe past 10 years seemsto indicate no
noticeableeffects of their exposure on fertility. The

50 births represent a rate of 61 per 1000 population per annum comparedwith 37.3 for the Marshall Islands (1957). The incidence of miscarriages
andsézl/births in these exposed women wasabout
twice that in the unexposed women during the
first 4 years after exposure, but no difference has
been noted since then (see Table 8).
A cardiovascularsurvey of the adults (1959)’ showed

no outstanding differences between the exposed
and unexposed groups. The Marshallese people

appeared to haveless hypertension on the whole

than is noted in people in the continental United
States.

An arthritis survey (1959)’ showed no greatdifferences between the exposed and the unexposed
people, and about the sameincidenceasis seen in
American populations.
Ophthalmologtcal surveys showed no remarkable
differences between the exposed and unexposed
groups except possibly a slightly greater numberof

cases of pterygia, pingueculae, and cornealscars

in the exposed groups. It is not known whether
these findings are of any significancein relation to

their radiation exposure. Slit-lamp observations
showed no opacities of the lens characteristic of
radiation exposure. As a whole, visual and accom-

modation levels in the Marshallese appeared to be
above the average in the U.S. population.

Dental surveys’ showed nosignificant differences

in caries rate between exposed and unexposed
groups. However, the incidence and severity of
peridontal disease wasslightly greater in the exposed group.It is not known whetheror notthis
finding is related to radiation effects. The poor

oral hygiene generally observed in the Marshallese
hadits usual results, namely, high caries rate in

teen-age children, severe peridontal lesions in

adults (heavy calculus and loss of alveolar bone),

and edentulous mouths in the aged. Radiation ex-

posure did not appear to haveaffected developing

dentition in the exposed children.

Aging studies were done in which various param-

eters usually associated with aging were measured

or estimated on a 0 to 4 + scale (skin looseness,
elasticity, and senile changes; graying of the hair
and balding; accommodation, visual acuity, and
arcus senilis; hearing; cardiovascular changesin-

cluding blood pressure and degrees of peripheral

and retinal arteriosclerosis; neuromuscular func-

tion; and hand strength). Comparison of these
measurements in exposed and unexposedindivid-

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