eee
lr
4
*
~
:
ALAMOG SCIENTIFIC LABORATORY
UMIVERSITY OF CALIFORNIA
Loe ALAMOS. NW MICO
OFFICE MEMORANDUM
Dr. T. L. Shipman - H-DO
Cc. C. Lushbaugh
. SUBJECT:
SYMBOL. :
DATE:
BIS
AO O for
sual sad
May 23, 1957
ADMINISTRATION OF Cr°! TO VOLUNTEERS
H-4
|
mower tana Lami
|
enamel
we
we”
men. Gel Scat
enam ut
.
:
Shed eg
—
_
—
As you know, we are planning this summer to sake an_
extensive study of the use of radioactive chromium as a tag
upon the living circulating red cell is man and experinental
animals.
In particular, we wish to study the applicability
of the whole-body counter to this technique.
The only method
available at the present tine requires withdrawing multiple
blood samples, which require extensive technical manipulation
and give a decay curve which is extremely difficult to inter-
pret in the sick person.
Since-the whole-body counter would
measure the entire body's retention of chromium and since the
evidence indicates that the retainedchromium is on the red
cell, the whole-body counter shouldbe able to make a determingtion in 100 seconds that at the_present time requires a
technician several hours to couplete.
For this purpose, we
plano to tag the red cells of about ten normal persons and
about ten patients.
Dr. Murray Friedman ofSanta Fe, whose
son Harold will be working with us, is trying to obtain patients
from all over the state with various blooddyscrasias.
Dr. DeBriere of the Los Alamos Medical Center assures ne
that the Hospital Bed Fund of the Los Alanos Medical Center
Women's Auxiliary will attempt to defray the hospitalization
costs of the out-of-town patients.
The Special Stidies Labora-
tory of the Los Alamos Cancer Clinic will perform-—the controlling
hematological studies, so there should be no clinifil costs
accruing from this study.
Drs. Robert Grier, Paul Lee;—Charles
Shafer, and Sidney DeBriere have agreed to help se with these
FILE BARCODE
REMARK
80131830
BP
(|
a {. t
4
—
00131830.001
BEST COPY AVAILABLE