No sperm was encountered within the
Number of Spermatozoa (//mm?}
spermia was found in 16 cases in November 1954,
e.g. about 8 months after the detonation. Both
lowering of motility and morpholovical abnormalities of spermatozoa were also observed.
The testicle of the fatal case, which died
206 davs after the explosion, was remarkably
atrophic. possessing the interstitial tissue composed
of loosely arranged connective tissue.
Spermatogonia were greatly decreased in number,
and in some areas they were completely lacking.
lumen
deb
1954
of either seminiferous tubules or epididymis.
Indications of recovery were observed at about
one year after the explosion in some patients,
but number of spermatozoa was still far below
normal value in all the cases. Most of them
began to reveal a sign of regeneration about 2
years after the exposure, and got children (Fig.
Fig. 5.
5.
=!
TOT
1955
bu dds i
1958
1959
a
1956
1957
Changes in the Number of Spermatozoa
Liver Function
Slight disturbances of the liver function were
found in a few cases about + weeks after the
initial exposure. Later it became more obvious,
i.e. the repeated appearance of jaundice in several
5 and Table 2).
cases, an increase of serum gamma-globulin conTable 2.
Date
Case
“M (2)
3
M (2)
5
6
7
M (4) |
M (3)
|
2
3
|
:
f
|
M
|
6
7
M) m
|
8
9
10
Mt
M (3)
M..--- Marriage
‘
M,
f
|
M
|
|
in|
|
f |
|
ms
2
/
M
M
M
f
{
A
Assen Abortus
"95
m
m
25
24
m
22
M
m
f
t
f
!
|€
Crete No. of children at the time of exposure
freee Female
26
22
f
M
f
M
f
M
of
m!
f
97
oM
|
m,
|
30
28
t
!
M
| M (2)
15
16
Meee Male
,
!
|
M
28
|
m
4
5
38
i
M
M
K-i
+14
Age in
7
"i
OA
M (3) |
8
12
13
’
)
"
:
_
; 1954
1955
1956
1957. 1958 , 1959 , 1960 . 1961 || 1962 | 1963 || March 1954
|
|
|
|
T-1
2
Marriage and Childbirth of the Patients
a
'
fie Fatal case
|
mi
26
18
23
m
22
24
m
23
18
22
39
97
20