These signs reached the peak in about the 3rd4th week and subsided gradually. These skin
lesions including epilation were observed on
parts of the body not covered by clothing and
on the navel region where radioactive custs
from neck were deposited. Elistologically, these
skins were similar to ordinary cadiccdermatitis.
Remarkable epilation was observed in 20 patients.
Two patients who did not wear hats at the ctume
of the accident revealed complete epilational
necrosis. Aficroscopically, coagulation necrosis
and cell infiltration in the necrotie scalp was
observed at about the 4th week. Vhese skin
lesions recovered gradually, Thin and delicate
hairs began to grow again at the beginning of
Mis, and in 2-3 months they grew back almost
completely. But. T-2 and T 7 have alopecia
even now. In some persons, capillary dilatation,
depigmentation and pigmentation of skin are still
observed m= the navel region. For the skin
lesions cvery possible treatment was applied.
For decontamination, mechanical washings with
Na-EDT A or warm water were done. The hair
of head, axifla and pubes was shaved off. Vhe
nails were cut off. In one and half months
superficial contamination was almost removed.
The distribution of surface radivactivity and
skin lesions is shown in Fig. 20°

Radostrye Contamination

Rudiodermatitis

3. Haematological Observations
Leucneples
Total number of leucocytes decreased gradually, showing minimum count at about 4-8 weeks
after the exposure. Five cases revealed a count
of less than 2,000, mm’, thirteen less than 3,000,
andfive less than 4,000.

In one case, the leucocyte

level depressed to 800. A correlation was found
between these minimum count and the doses of
individual external irradiation.
Neutrophil level also depressed. Between the
tth-8th weeks all of the cases got minimum
values, which were proportional to the dase of
radiation received (Vig. 3). In most cases a shift
to the left of the nucleus was observed.
Lymphopenia was noted between the 2Ind-8th
weeks in all cases,
Leucocyte count began to inerease since 8th
week, At that time, metumyelocytes and myelocytes appeared in peripheral blood of some
cases.
In most Cases eosinophilia and in some cases
monocytosis were remarkable, especially with
the indication of recovery. Eosinophilia continued in some cases for several years without
proof of parasite.
Neutrophil and lymphocyte levels recovered
gradually.
However, cumulative distribution
curve of total leucocyte count at the 6th year
was still slightly displaced to the left of normal
Japanese, and in several cases, number of lymphocytes was below 2,000,'’mm/’.
Motility and phagocytosis of neutrophils depressed remarkably. Although they recovered
gradually, after one year these functions in some
cases were still loser than in normal persons.
Erythrocytes
At the time of hospitalization, a few patients
were slightly anaemic (RBC 3,000,000, mm’).

se

wot

ne,

gs

Morked

Moderate

Slight

Ulcer

Fig. 2.)

we

Erosion

ee

Erythema

Epilation

Distribution of Radtodermatitis!!

No

reticulocyte was observed in them at the critical
stage. The cumulative percentage curves changed as in Fig. 4.
Colour index was higher than 1.0. The PriceJone’s curves of erythrocytes diameter were
displaced to the right of normal one at first,
and returned to almost normal after one year.
These changes corresponded to changes of erythroblasts diameter in bone marrow.

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