TR eR At we neat LE eet net th

Conard

ie te tata i Aae SaAT TE

Effects of Ionizing Radiations

492

mer

PERCENT AGING

30}-

20

30

40

50

60
AGE

70

8&0

90

Fig. 2. Combined weighted data (coefficient for age correlation of each criteria used
to weight scores before summing). O Exposed, @ unexposed, 0 combined with standard
error means. r = 0.99 (correlation with age significant at 1% level), y = 0.51 + 0.38 x
+ 0.01 x3.

though many of these criteria showed good correlation with age, no radia-

tion-induced aging effects were detectable since there were no significant differences in the exposed compared with the unexposed groupsin these studies.

By combining data on a percentage response basis it was possible to obtain a
‘biological age score’. The lack of correlation with radiation exposure with

such scoring in the Marshallese is demonstrated in figure 2. Perhaps these
tests were not refined enough to detect aging effects of irradiation since such
changes may be too subtle to be detected in this manner. In any event, most
of these criteria are probably not associated directly with lethality.

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