Nuclear Medicine Technology and Other Health Applications Extension and Improvem-:nt of Radiographic and Isotopic Project Title: Diagnostic Techniques RX-02 -03-(c) 13. Publications: J. S., Fairchild, R. G, 2, Radiology 104, No, —_—_ and Atkins, H, 393-8 (1972). L. Dosimetry of ~ SL > wt Robertson, californium 252, 7 Fowler, J. S. A new synthesis of unsymmetrical azo compounds. Chem. 37, 510 (1972). J. Org. Y/, bod. / Atkins, H, L., Christman, D. R., Fowler, J. S,, Hauser, W., Hoyte, R, M., Klopper, J, F., Lin, S, S. and Wolf, A, P, Organic radiopharmaceuticals labeled with isotopes of short half life, V, 18p_ labeled 5- and 6- fluoro- | tryptophan, P, J. Nucl. Med. 13, 713-9 (1972), Atkins, H. L., Eckelman, W, C., JL3 § Hauser, W., Klopper, J. Splenic sequestration of 99MTc-labeled red blood cells. 13, No, ll, 811-4 (1972), Hankes, L. V., Leklem, J., Brown, R, R,, Mekel, F. and Richards, J, Nucl. Med, jiC2L R. C. and Jansen, Abnormal tryptophan metabolism in bantu with scurvy-type skin, Med, 7, 184-9 (1973). Atkins, H. L. and Klopper, J. F. Atkins, H. L., C. R. Biochem, AAA Measurement of thyroidal technetium uptake with the gamma camera and computer system, J. Nucl, Med, (in press). Eckelman, W. C. , Klopper, J. F, and Richards, Vascular imaging with ??™c-red blood cells, P, Radiology (in press), JE 72S YL 933 Atkins, H. L,, Fairchild, R,. G, and Drew, R. M. Biological properties of 252cf, Am, J. Roentgenol. Radium Therapy Nucl. Med, (in press), jlok2 Atkins, H. L.,, Klopper, J. F., Lambrecht, R. M. and Wolf, A. A comparison of technetium-99m and iodine-123 for thyroid imaging. P. Roentgenol. Radium Therapy Nucl, Med, (in press) Atkins, H. L., Klopper, J. F., Eckelman, W. C. and Richards, Am. Jeo... (9sé- P, The technetium-99m-DTPA renal study. Presented at the LAEA Symposium on Radioisotope Scintigraphy, Monte Carlo, October 1972, jo, +2 a 14, f — i200 Word Summary: hae ere are two main objectives in the various studies carried on in this budge ivity: development of diagnostic agents for clinical application to human diseases; and reduction of radiation dosage in nuclear medicine examinations, The major health problems in which nuclear medicine techniques can improve diagnosis and reduce radiation exposure are heart, neoplastic diseases, The studies, pulmonary and centered on radiopharmaceutical development, necessitate extensive interdisciplinary collaboration, (See Continuation Sheet) Pi 19215 RX-57