ee Song Nuclear Medicine Technology and other Health Applications Treatment and Biochemical Dissection of Parkinsonism and ESHPS 2 weenie? on ' J ‘ ” ‘4 Project Title: 13. Allied Conditions RX-01-03-(a2) Publications: Cotzias, G. C,, Tang, L. C., Miller, S. T., Sladic-Simic, D., and Hurley, L..S. A mutation influencing the transport of manganese, levodopa and tryptophan. Mena, Sci. 176, 410-12 (1972). 13.00 I., Lopez, G., Horiuchi, K., and Croxatto, H., Jr. of newborns of levodopa treated rats. Low viability Nature, 239, 285-7 (1972). /0303 Cotzias, G. C., Lawrence, W. H., Papavasiliou, P. $., Duby, S. E., and Mena. I. Apomorphine and parkinsonism. Trans. Am. Neurol. Assoc, (1972). 97, 156-9 ~/6¥9 Papavasiliou, P. S., Cotzias, G. C., Duby, S. E., Steck, A. J., Bell, M., and Lawrence, W. 88 cas72). H. Melatonin and parkinsonism, - J, Am. Med. Assbc. 221, No.1, JL698 Cotzias, G. C., Tang, L. C., and Mena, I. Effects of inhibitors and stimulators of protein synthesis on the cerebral actions of levodopa. Neuro_sciences Research, I. J. Kopin and S. Ehrenpreis, Editors, Vol. 6, Academic Press, New York, 1972 (in press). /6 7 Duby, S. E. Cotzias, G, C., Papavasiliou, P. S., and Lawrence, W, He Injected apomorphine and oral levodopa in parkinsonism, Arch. Neurol, 474-80 (1972). | Cotzias, G. C., Lawrence, W. Nicotinamide and parkinsonism. R. J. Soc. H., Papavasiliou, P, _ /bI7¢ S., and Duby, S. New Engl. J. Med. 287, 147 (1972). E. J 7603 Ginos, J. Z,, LoMonte, A., Cotzias, G, C., Bose, A. K., and Brambilla, Synthesis of tritium- and deuterium- labeled apomorphine. J. Am. Chem. — (in press). J7/SS Cotzias, G. C. Controlled double-blind studies of drugs. Cotzias, G. Metabolic responses to levodopa. Med, 287, 937 (1972). C. 287, 1302-3 (1972). Getzias, G. C., Papavasiliou, P. S., and Mena, I. park® ism. J. Am, Med. Assoc, 223, No. Setzias, G. : New Engl. J. Vd New Engl. 1, 83 (1973). ‘Sie: . 27, | d- / 7245 L-meta-tyrosine and /73 oy . C. Levodopa and related drugs. The Medical Letter (in press). Gillespie, N. G., Mena, I. Cotzias, G. C., and Bell, M, A: modifying responses to levodopa in parkinsonism. J. Am. Dietet. press). . (See Continuation Sheet) 1179193 J. Med. 7/730} Diets for Assoc, (in {73> f RX-35