Biological Studies of Materials Arising from Energy Operations Free Radical Studies on Mechanisms of Action Project Title: of Pollutants 18, Expected Results in FY 1975: RX -03-06- (a) (Cont'd,) If evidence is found that combination is by means of free radicals, the reaetions will be studied by stopped-flow techniques to obtain preliminary data on the kinetics of reaction, and electrochemical measurements (cyclic voltammetry, potentiometry) will be used to delineate oxidative reaction paths and potentials in different solvents. The setting-up of an "on-line'’ EPR spectroscope at the Dynamitron, and installation of ancillary experimental apparatus would begin in collabor- ation with the Chemistry and Physics Departments, 19, Description and Explanation of Major Materials, Equipmenc and Subcontract Items: é V—— ‘ FY 1975 Capital Equipment: Additional equipment for full implementation: EPR spectrometer with Q-band EPR bridge ($00,000). 20. Proposed Obligations for Related Construction Projects: None RX - 384 1419321