Appendix V Findings of Epidemiological Studies of Cancer in Irradiated Populations (From J. Shapiro, Radiation Protection, pp. 260-4, Harvard U. Press, Cambridge, MA, 1972) No Observed , Subject of study t Hiroshima and Nagasaki A-bomb survivors (bomb exploded 1945) 2 Hiroshima and Nagasaki A-bomb survivors twomen) Wanebo Brillet al etal Dove No ot Form of in exposed tine tyr (Roe rads) persons? cancer group” exposed’ Leukemia Leukemia Z| 6 iv | 30 S.J 4 O-20 21-80 [3-2] 196% (238) 8S 070 13 184 _ 4 Japanese V-homb survivors ex posed within F400 m of detonution lied 19SO-19621 Angevine and Sablon S Children exposed prenatally due to abdominal v-ray to mother cee posed 1945-196 and died hetore Jablon and Kato 10 ionmot BI LO x 49S Leukemia a4 20 o-u 1Q.34 3.082 | 262 Breast cancer Breast cancer 3 4 73 3 40-K9 IU-199 “67 xO2 Breast cancer Breast cancer 2 < 2 : 200 xd] Breast Ganecer 6 23 x40 Hreast cancer 2 23 Cnexposed eontrol LASX Breast cancer 2 6 | “eh S00 person-rads! 1292 Sih cancers I wits I 21s subopsies Alb cancers cucept leukemia Unknown Hiroshima and Nagasuki A-bomb SUPVIVOFS Exposed prenatally Expected Follow-up 14962 (81) 3 ~ does 1970 693) * el Ses ” 198 146d (095) end of 1988) ai 6 Uo bho Leukemia 443 77 DO0F . All cancers Court Brown et 1960 0 239) Children exposed prenatally (horn in 1987-1) 984 and died betore end of 1960) MacMahon '962 6240) 7 : Intunts who received itradtution of yeas 61 600 Lower dose chest before age @ mo in treat ment tor enlarged thymus (treated Rroup 2.207 1926-1987 follow-up in 196s) Hempelmanniet al 1967 (1460) XS 60 hy roid 4 1) ()7 Thyroid (benign) feukemta A 3 xO 1348 Eby roid 14 Ob Thyroid (bent 1s 60 boukema i a Phyroi carcinoma Q (43 Leukemta 0 ous (32 226 per. son yrat risk! fligher dose group 40x ChE AXS person veal risk! % Intants irradiated routinely with 10-20 X-rays Co anterior mediastinuin 140], mostly £30 inciud- through small id X 4 om? purl ing 244 duys ufter birth gs Uupparently harmless and perhaps beneficial procedure (x-ray LY38-46 fol with en larged thy mius low-up 19S6-38)) 1960 (146) 4 78-450 Contre et al Chudren tredted with «-rays to hesad mesk of chest for vartous ats isiuy benign conditions maginty “en lurged © thymus and adenitis treated before age lo and tollowed th age 230 Saenger et “S014 ) SO 20013 lL nad 3 Dhserod Thv rout thenign) i 0 ° iv) LOU HOO L338 al, 1960 (292) tO) Children treated betore age 16 with Upta 2% Not given x rays tor enlarged thymus pertussis and head und neck diseases and died betore age 23 treated 1930 1986. toilowup 1440-19561) Murray ef al F989 Cl4h5 - 134 - VR7D Leukemig is