2

Mater teehee

t

‘

x

:

Cote,
we
4

my

Isisini te nolaserd eda to m3 omt3 ynta 38 901319391 ybod 9» usiw

time post onset of: uptake, days,

fone at,

ad

d

inetantaneous fraction of stome decaying per unit time, day"!

pe

initial atom ingestion ‘rate, “atous day~?,
i”

s

instantanecus fraction of atoms removed from compartment. i by
enpeok ot

ce eames

tad?

i-0

amid

physiological mechanisms, day~*,

th Vaoavidun

PUIG UN Ted

ofl?

at

compartment i deposition fraction,

the number, of atémsin*compertmqnt ‘i*zelative,to the number in al!
"ys

i

compartments atthe onset of declining continuous uptake, (t=O),
a

vee

yeale

yoy

emi

ty.

;SPW ETB

PU tid

Wt

we)

instantaneous urine activity concentration, Bq at,
:

.

:

~]

un

fraction from: Gl, s¢ast , to bloods ( 4+.4,>

@eaten:

oe Do ausbt

subject urine excretion rate, & day™*,

fraction excreted by the urine pathway,

tods

oye

;
wy Gh

|

|

5

instantaneous fraction of atoms removed or added to the atom uptake
:
Coe Ebay b
Salas leagaipi of: Foe itudes
|
per unit time, day”, due to factors’ other than radioactive decay,

ve vie

.

;

instantaneous body burden, 5q,
sat

body burden at the onset of

:

eiqmeaye

‘uptake, Bq, —

sah

a yrrandtah

ae jg toe

+

oy

EP de

Hr Eg

the number of disintegrations in all compartments occurring ‘during
the uptake interval, Bq days.

oo

The development of Eqs. (1), (2), and (3) was based on the following cunvolution integral.

At some variable time, T, defined during a fixeduptake

interval, T, the daily activity ingestion rate crossing the gastrointestinal
tract to blood is given by

AEP

TET

ea

° e -(ketrA)T
E

*

Select target paragraph3