2
Mater teehee
t
‘
x
:
Cote,
we
4
my
Isisini te nolaserd eda to m3 omt3 ynta 38 901319391 ybod 9» usiw
time post onset of: uptake, days,
fone at,
ad
d
inetantaneous fraction of stome decaying per unit time, day"!
pe
initial atom ingestion ‘rate, “atous day~?,
i”
s
instantanecus fraction of atoms removed from compartment. i by
enpeok ot
ce eames
tad?
i-0
amid
physiological mechanisms, day~*,
th Vaoavidun
PUIG UN Ted
ofl?
at
compartment i deposition fraction,
the number, of atémsin*compertmqnt ‘i*zelative,to the number in al!
"ys
i
compartments atthe onset of declining continuous uptake, (t=O),
a
vee
yeale
yoy
emi
ty.
;SPW ETB
PU tid
Wt
we)
instantaneous urine activity concentration, Bq at,
:
.
:
~]
un
fraction from: Gl, s¢ast , to bloods ( 4+.4,>
@eaten:
oe Do ausbt
subject urine excretion rate, & day™*,
fraction excreted by the urine pathway,
tods
oye
;
wy Gh
|
|
5
instantaneous fraction of atoms removed or added to the atom uptake
:
Coe Ebay b
Salas leagaipi of: Foe itudes
|
per unit time, day”, due to factors’ other than radioactive decay,
ve vie
.
;
instantaneous body burden, 5q,
sat
body burden at the onset of
:
eiqmeaye
‘uptake, Bq, —
sah
a yrrandtah
ae jg toe
+
oy
EP de
Hr Eg
the number of disintegrations in all compartments occurring ‘during
the uptake interval, Bq days.
oo
The development of Eqs. (1), (2), and (3) was based on the following cunvolution integral.
At some variable time, T, defined during a fixeduptake
interval, T, the daily activity ingestion rate crossing the gastrointestinal
tract to blood is given by
AEP
TET
ea
° e -(ketrA)T
E
*