AAP,
aN

attin

irradiated mice had opacities detectable with the slitelamp.

The rate cf

propresgion of the opacities varied directly with the dose (Chart 1).

Lens

damage was nore severe for 2 given dose of neutrons than for camxparable doses

of ge-ma rays; thus, in cataract. induction approximately 100 rep of neutrons
corresponded to about 650 r of gamma rays (nee = 6.5).
Systenetic studies of the eye disclosed a resarkable change of the iris
consisting of prorressive loss of iris tissue, as illustrated in Fig. 1.

This

process appears to be an abloatropry apparmtly hereditary in this strain, as
mild atrophy of the iris occurred In aging nonirradiated contrels; like

cataract, however, the degree of atrophy was significantly greater following
irradiation, in proportion to the dese.
Greying of the fur saa noted as early as 3 months! pestirradiati on,
progressing with time as a fmetion of the dose (Chart 2).

It varied with

different anatomical regions bot in certain areas was sufficiently weil
correlated with the dose te constituta a simple, though only approximate,
biclogical dosimeter.

DO ARCHIVES

Select target paragraph3