Subject No. 2125. This patient died in 1987 from carcinoma of the lung with brain metastases at age 70. He had been referred to a Honolulu hospital for evaluation of guaiac-positive stools in October 1986. A chest x-ray was negative at the time of referral. No serious problems were detected during his Honolulu examination, but respiratory symptoms from the tumor developed in January 1987. He had beena cigarette smoker, and was felt to have severe chronic obstructive pulmonary disease with recurrent bronchitis. Subject No. 2128. This 39-year-old woman had diabetes mellitus complicated by chronic renal failure, severe diabetic retinopathy and neuropathy, and anemia (hemoglobin 9.4 g/dl in October, 1984). She died in a Honolulu hospital after emergency air evacuation from Utirik. Diagnoses made at the hospital included hypoglycemic and hypoxemic brain damage, diabetes mellitus treated with insulin, anemia secondary to renal failure, and sepsis. Subject No. 2164. “Postpartum hemorrhage” and “uterine inertia“ were listed on the death certificate of this 42-year-old womanin February 1985. Previous problems included obesity and possible gout. A blood count in March 1984 was normal. Subject No. 2189. This 59-year-old woman died in 1987 from chronic renal failure due to diabetes mellitus. Her serum creatinine in March 1986 was 10.9 mg/dl and the hemoglobin level was 7.7 g/dl. Subject No. 2200. “Inanition” and “senility” were the death certificate diagnoses for this 72year-old woman who died in December 1985. A thyroid nodule had been noted at least since 1977 but the patient “appeared to be a poor surgical risk.” Her hemoglobin level was 11.6 g/dl and the white blood cell count was 6,200 perul. A left breast mass had been noted since 1966, but the patient had declined biopsy and surgery. She said the mass had been present since youth. Subject No. 2212. This 66-year-old woman died in 1987 from chronic rena! failure due to diabetes mellitus. She was evaluated at Kwajalein hospital in 1985 and noted to have renal failure, hypertension, and anemia. When evalu- ated by physicians of the 4-Atoll Healthcare Program she was notfelt to be a candidate for dialysis, and her family agreed to supportive management. Subject No. 2218. The death certificate diagnosis on this 34-year-old woman in September 1985 was “congestive heart failure.“ When examined in March 1985, the only significant abnormality had been a urinary tract infection for which she was given an antibiotic, although asthma had been notedin the past. The patient was late in pregnancy at the time of her demise and was, on thebasis of history obtained from the 4-Atoll program physicians, probably eclamptic. Subject No. 2249. This woman died at age 57 in February 1986 from complications directly arising from local extension of a “malignant meningioma.” A description of this patient and the tumor was presented in a previous BNL report (Adams etal., 1983) following the original diagnosis in 1982. Comparison group Subject No. 814. The death certificate diagnosis in June 1985 for this 33-year-old man was pneumococcal meningitis confirmed by culture. He worked on Kwajalein and died in Kwajalein hospital after being transferred from Ebeye hospital. His most recent BNL medical examination had been in April 1983, when problems of smoking and héavy alcohol consumption were noted. His blood count was normalat that time. Subject No. 821. This 38-year-old woman died in 1986 from complication of childbirth, her death certificate diagnosis being “postpartum hemorrhage.” When seen in April 1986 she was 22 weeksinto her thirteenth pregnancy. Nosignificant abnormalitites were noted at that time. Subject No. 842. The death certificate diagnosis on this 61-year-old man in March 1986 was “liver failure due to hepatoma.” The only active problem notedin his last BNL medical examination in March 1985 was chronic lowback pain. A routine sigmoidoscopic examination was normal except for the presence of hemorrhoids. Hepatitis B surface antigen was not detected in his serum, but antibodyto the surface antigen was present. Subject No. 846. This 63-year-old woman underwent a bone marrowaspiration in March