and cases Hematological Effects on Heavily Irradiated Japanese Fishermen 69 expos ; Cronxrrg etal ed by T€actor ac. Ov, 1956 A "9 1956; Hasrenr; 106, Critical 196} .2 * sitnilar y reveoie €aled et al. - nol (weeks =oy 4-7) Ica] staSe = 40+ ; he DUNimal] Is ere cas “4S and reticulum 7aSes, OMparing 5 70} ce : 1! €s, which . y,; Fgure Fig. 4 Leukocytes of Bikini patients g With Dorma] (J) a Segre . t EPPbears ifd Pod E 30} uu a ol i ep (cumulative). x! a “ f : on - «.™°s . ™ 7 7 e ° & oF . Pio aA #* 3 Sf 2 3 3r 2r a, Ty ye # x19: 0 4 . ve < = OF & at . at 5th week ) ! . Wi YT astic and n = : the then be tu ca ; gin gulieeerereerdinrn an 5 ahably. After one 701 Persons 2 Curves of leuko. the left of the 5 ightly to the lefe demi Cy be i =~ = 8 7 . a f : o ~. Fig. 5 E 57 = 4t- Changes in the numberofleuko- cytes, neutrophils and lymphocytes. 7 ao a 3 oA LY P=, ‘bof fom . 0 7 1421283 4249556370 “6 612345678 9101112191815 days months years time after exposure 2 lf He of normal Japanese. In the case of erythrocytes, 2 years after the exposure, the curve approximately came back to normal. A similar tendency is seen in the cumulative distribution curves of platelets. a the changes of total leukocytes, neutrophils, and lymphocytes of 2 cases which Si+ °n an an “, on lob = 9} 3. 1S, toxic 8ranulat; ° totic 40no0 b ulations lities of Mark, * oO 12 Stage, ed * Nuclear de bris 7F it x103 72D 9 at the crit; oa aplastic i ee + . 2 5 preheat 2st 74 Ss 6F Overy was Not med ITOWw wa n Complete @mined lee wa LOOP Se ierved, sh rob mn eo . ” ¥ TE a po 70° 6a “WY 12+ ~~ 2 CA ; Se ~*~ BE 3 7r gaae ny. Oe 10 ry 1O- =, SSS ~- [ee 12+ Pr o3 hae Jo 7 or x10? x * . a 1234567 8 9 10111213 ¥ ° et ° *: fe control i s va ee a wfenscnn eres 1 year leukocytes 10? eS Spe ” t Br L . = -.. ss ° we 3 sol 1n sey, n . months es t = me a : However, in a Few cases slight 5 shows & neutropenia P is still observed. Figure & . oe are representative for severe injury. A small increase of “‘mitotically connected abnormalities”, i. e. karyomeres of erythroblasts, were observed in bone marrow smears of a few cases alter = 10 years. -_ . “ results are summarized as follows (IsHiHAna and Kumaton 1965 ; 1967; 1969). = -_ Cytogenetical studies have been performed since several years. The 1. The frequency of aneuploid cells was 2~3 per cent, which was not We. oe - . toe SOT: imalt lay ce ee wr Pd “ : rT. ae . a et bye e Oe Fe Se gl edBan LE 29h Feed th ef ae 2 ahe tatwtb? ‘x meh en at ig Le retSee ke rm ee Pe ee a nT pe Oe