‘ -~ 17 - It would take 53,000 particles of the size illustrated in Table III to reach the MPLB of 0.016 uCi which results in’15 rem/yr to the entire (1000 g}) lung. However, as Table III indicates, these particles would irradiate only 3.4 g of this 1000 g to the lung, but at a dose rate of 41000 rem/yr-. Thus, as Table III indicates, these particles result in an intense but highly localized irradiation. fundamental question is, then: A is this intense but localized irradiation more or less carcinogenic than uniform th ~ ot pee ivraciation? Alternatively, rradiation equal the remainder of this to, is the DF for this particular greater section, than, we or less than one? review the guidance, more apsropriately lack of quidance, c eOrm In or for dealing with this hot varticle orceplenm. 22/ Geesaman, Donald P,, UCRL-50387, pp. 8, 15. 22 Langham, wright u., The Problem of Larae Araa Plutoniun Contamination, U. 5. Dent. of H. E. W., Public Heaith Services, Seminar Paper No. 002, Dec. 24/ Long, A.8B., 6, 1963, p. 7. "Plutonium Inhalation: The Burden of Nuclear Mews, June 1971, po. Fl. eslicible Consecuence," oO tly tv cb wort 25/ Geesaman, Donald P., UCRL-50387, np. 8, 15. Based on aman’s model for a lung at one-half naximun inflation. aman estimates a total of 688 alveoli at risk, each -§ om3 in volume, and deep respiratory zone tissue density .12 gfenm?. 24/ See footnate 23. zi’ Based on a lung mass of 2 standard man = 1000 g. 2t/ my: A. : . = This assumes that the radiation field of marticles do not overlap. 4h the 53,000