r
-
26
=
involved, surface doses of 16,000 rad from a P32 plaque
induced an average of 1 cancer/animal which is indicative
“nat larcer manmals are similarly susceptible to skin cancer
azter intense radiation insult.
Again, these gross obser-
vations demonstrate that enhanced tumor incidence does occur
after very hica doses.
Intense localized radiation of the subcutaneous and
intraperiteneal tissue of animals by Pu-239 has also been
snown to cazse a high frequency of cancer induction43-45,
NoW what are these exneriments trying to teil us?
results
I=-
Certainly a reasonable interoretation of these experimental
§:
when
a critical
(e.c., a hair follicle)
sosage,
architectural
unit of a tissue
is irradiated at a sufficiently high
the cnance of it becoming cancerous is approximately
‘
19-3
t9 1077.
This has become known
as
the
"Geesaman
-*
3
Palztesc Human Exserience
- Since in2 above experiments relate to cancer in¢uction
in animals,
t4/
iz is pertinent to ask whether man is more or less
Sanders,
C.L.
an@ T.A.
Jackson,
“Induction of Mesotheliomas
andi Sarcenas From ‘Hor Spots' of Pu? Activity," Health Physics,
ecol. 22, No. &, June 1972, op. 735-759.
"Carcinocenic Properties of
3
and of
mp.
Plutonium,"
361-363.
Radiotogy,