Laskin, et al, indicate a significant carcinogenic response
in the lung at 1400

.

5G

t

.

oss

Gcesainan indicates

lung is of

~

suggesting a comparable sensitivity

-

of lung tissue”™”~.
time in the

rem,

.

“

.

;

the order of cne vear™’.
Rh

;

that the tissue repair

ro

5

7

.It therefore

seems appropriate, but not necessarily conservative, to accept
as guidance that this enhanced cancer risk cccurs when particles
irradiate the

surrounding lung tissue at a dose rate of 1000

rem/yr or more.

TABLE IV

Particle Activity and Size to Give a Dose of
ral

2060 rem/year to the Surrounding Lung Tissue
Particle

Particle Diameter

npc)

239 Bu.

alveoli)

0.14

0.8

0.12

1/2max inflated ( 68 alveoli)

0.07

0.6

0.09

Closest 20 alveoli

0.02

0.4

0.06

3/4

max

intlated

56/

Laskin,

57/

Geesaman,

58/

Ibid

(138

.

et al, Op.

(u)??

238pu0>

cit.
ll.

cit., p.

Donald P., UCRL-50387, Op.

Based upon specific activity given by Langham, W.H.,
59/
Op. cit., p. 7.

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