-~17- It would take 53,000 particles of the size illustrated in Table III to reach the MPLB of 0.016 uCi which results in 15 rem/yr to the entire (1000 g) lung. however, as Table III indicates, these particles would irradiate only 3.4 g of this 1000 g to the lung, but at a dose rate of 4000 rem/yr-®, Thus, as Table ITI indicates, these particles result in an intense but highly localized irradiation. fundamental question is, then: irradiation more or irradiation? less A is this intense but localized carcinogenic than uniform Alternatively, is the DF for this particular form of irradiation equal to, greater than, or less than one? the remainder of this section, we review the guidance, more appropriately lack of quidance, In or for dealing with this hot particle problem. 22/ .Geesaman, Donald P., UCRL-50387, pp. 8, 15. é 23/ Langham, Wright H., The Problem of Large Area Plutonium Contamination, U. S$. Dept. of H. E. W., Services, Seminar Paper No. 002, Dec. 6, 24/ Long, A.B., 25/ Geesaman, Donald P., Public Health "Plutonium Inhalation: 1968, p. 7. The Burden of Negligible Consequence," Nuclear News, June 1971, p. UCRL-50387, pp. 8, 15. 71. Based on Geesaman's model for a lung at one-half maximum inflation. Geesaman estimates a total of 68 alveoli at risk, each 8x10-6 cm3 in volume, and deep respiratory zone tissue density of 0.12 g/cm. 26/ See footnote 23. 27/ Based on a lung mass of a standard man = 1000 g. 28/ This assumes that the radiation field of the 53,000 particles do not overlap. so et . Serhan ee od oy . . we 1 oN i et oo . soe Lo Om DOS A aea tras sn a . Le ak “ 7 ' e! ty ‘ cof her ty% stp, TR pt a dee fe. - te" 4sne . aes: Boo te ve OS say)? wee . t “fe, a aR meget ge Tee “ale +, BE GT Ae. TOT ee ae a. : t ~~? ¢ “hot . one 4 . De “