4.
Reticulocytosis (reticulocytes above 2 per cent).
5.
Usythrocytosis (ROC over 5.6 million per c.rma. or hemoglobin over
13.0 52./103 cc. blood).
Wilidams has anlyzed the value of biood studics and protection against radiag
tion injury and has concluded that
numcsous routine counts are unnecessary where
good control of all circumstonces is maointaincd.
Nowever, in radiation areas,
more hishly controlled henatolosic studics arc needed in order to obtain more information on the threshold and pesmissabie values.
Kolde cnd Wahlbers have
analysed the lowering of the Lcubkecyte count in human beinss produced by minute
amounts of whole-body radiation.
They have utilised a statistical analysis.
Al-
though the mean Iecurocyte count 35 unchanged, the dispersion around the mean is
considerably deczcased by low exposure to izvadictien, thus making it possible to
use this statistical paranctes as on indicatica of izrzadiatica
moosure.
A complicating obsorvatieon is that of Wald ct al. who bas observed in the
control populaticn in Japan that was not exposed to cadiation of the atomic bonbs
that there has been a procressive decrease in the Leukocyte count over a period
of the dest ten years.
The scasons for this change ase obscure but obviously con=
plicate the analysis of chronically exsesed popuiations.
8.230
Evaluation of
Diced Chances.
The above criteria cesult fron cithor a depression of of on inereased
lability of hematopoiesis.
The estebiishzuent of the presence of these criteria
con be sscatly assisted by performing
paraiiel studies on comparable groups o
vumaa beings who ace tmown not to bo ettposed to radiation or any other toxic
asent.
Statistical comparison of the potentintiy exposed control group will heip to deter-
ca.
counts of the suspected srcup
counts.
In a similar manner the
or incivicual con bea compared to the post-es:posure
If there is a sicnificent chance in the Aattes, one can state with some
certsinty that there kas been emcessive omposure to some tomic agent.
soo 111d
pre-e:posure
A good