graph3 demonstrate the phenomenon called "coastinse” in which the white biood count
py dis discontinued.
Mayncord has shown that re-
gated small exposures to x-ray may couse more complete end long-lasting damage to
tha bona masrow than a sincle exposure.
Tae
¢ehanges induced by chronic low intensity exposure to ionising radiation
will be considered in the section on ¢he detection of exposure to ionising radiation.
8.6.3
varicd.
Mozpholosy of Bileod Celis.
Morphologic changes in tha leukocytes are
Dagenerating Iymphocytes arc secon in the circulation,
Lymphocytic nuciei
may be fragmented, pybnotic, clover-shcoped or only the usual nuclear pattern may
be altered.
Nucileoli may become very prominent, presenting the picture of "cwl's
eye nucleoli" (Wasson).
Large phasocytic mononuclear cells may be seen containing ©
nucieas masses ond occasionai red celis.,
excessively basophilic.
The cytoplasm of the mononuclenrs may be
YVacuoles may appear.
Inmature celis may be prescat.
generating granulocytes may be seen in the peripheral blood.
vacuoles and basophilia may be obsexved.
seduction in number.
Toxic granulation,
Piateicts show some chances along with a
Giant hyperechronstic pintelets are usually present.
kozyocytes kave been reposted as aopecring in the blood,
bicod smears of the Dikind animeis.
Dee
Mesa-
but were not seen in the
Supravitel stcins with Jenus gecen and neutral
red are reported cs demonstrating alterations in the mitochondria and neutral red
bodies.
Dickie and
Hompetmann have shovm that there is an increase in the nunbder
of refractitle acutsal red bodics of the lymphocytes of persons acutely and chronically exposed to ionising radiation.
These bodies are seen only in suproavitcl
preparation, asc not specific for sadintion, and were also seen in the lymphocytes
of persons working with
toxic choamiccts.
Bilobed lymphocytes have been reported in
the blood of human beings chrenicaily exposed to rediation and of humsn beinss
working around cycictrons (Ingram).
eccn.
Eypersegmented neutrophils have ciso been