s -€ COLOR PLATES : Plates 3.22and 3.23 show lesions at 53 days post-exposure. Plate 3.22 (X100, H&E) (Case #75) Loose lamination of stratum corneum with outward papil- lary projections und resultant ‘rugose’? appearance. Stratum granulosum of good width. Basal and malpighian layers distinct with pigment present. Slight edema of corium with mild tclangiectasis and slight increase im perivascular lymphocytes and pericytes. Small, atrophic hair follicle adjacent to sebaceous gland-— in mid pars reticularis. Plate 4.23 (X400, H&E) (Case #75) Same as 3.22. Occasional perinuclear cytoplasmic halos mid stratum granulosum. Loosely laminated stratum corneum. Pigment laden chromatophores in superficial corium along with occasional lymphocytes and mononuclear phagocytes. Plate 3.24 shows lesions (second biopsy) at 46 days post~exposure. : Plate 3.24 (X100, H&E) (Cause #39) Narrow rugose epidermis with papillary extensions downward of stratum malphigii. Latter are heavily laden with melanotic pigment. Slight telangicetasis of pars papillaris and pars reticularis of dermis. Occasional pigment laden chromatophores in superficial dermis, os ae , t z ; ‘ oad ~ _ ~ , ne, ree . . e ke ’ ;- . } f : - 1 . 60 oe ore eee o @ of soe a ee ee one ee eee . . . e ee . mer e ee eee ee eee ° o° ° ae oe 6 e . ese oe oe ° e a8 e Posner ee ‘ i