hyperpigmentation, The macules and papules (1 {62° min in diameter) usually oceurred in clusters and sometimes coalesced into larger lesions. ‘Che latter were cha ractertstically found on the sealp, neck, and the antecubital fossae. ‘The raised phiques varied in size froma few millimeters to several centimeters in diameter, were (hick, rough, dry, and hada deathery feel. ‘Phis type of lesion occurred predominantly on the feet and in the antecubital fossae and fo a much lesser extent on the neck. Areas of mcreased pigmentation also occurred on the ° bonbs, Crunk, and on the face. The majority of the lesions were superficial without blisters. A few days after appearance, dry, scaly desquamation occurred in the central portion of the hyperpigmenuted areas. The des quamation tefta pink to white epithelium nat remarkably different in texture from the surTable 3.10 LESIONS IN RONGELAP GROUP Type of Age 0-5 Age 6-15 Age 16 & Over ‘Total Group du ‘inte Media Ui of First Observation Lesion (13 people) C13 people) (38 people) (64 people) of Lesions * Per Cent of Total in Age Group having Indicated Lesion Bpilation { plus 7.6 38.4 [3.8 7.2 7 2 plus 3 plus 38.6 53.8 30.7 23.0 5.6 8.3 17.2 22.0 7 16 100.0 92.1 27.6 56.2 16 17 Total Skin Lesions Anus-Groin u.4 0.0 0,0 7.8 Seaip hoa.d 100,0 37.0 62.5 8 Neck G2 76.9 68,0 70.38 Zt Axtila Ol 7.6 15.7 23.4 2i 34.2 18.4 34.4 21.8 Antecubital eg Fossac Boas-wrists 30.7 30,7 “Feet 23.0 Arms 15.% Legs Trunk Nail Pigmentation 2. “OA4 23.0 53.8 15.3 53.0 45.3 4.3 10.3 - 28 33 28 12.5 31 7.6 23.0 7.8 aN 15.3 23.0 4.3 9.4 33 61.5 100.0 95,0 89.0 38 * Post-exposure davs. rounding skin. As the desquamation proceeded outward, the areas developed a characteristic appearance of a central depigmented area fringed with a hyperpigmented zone. Al a later stage, pigmentation began in the central areas and spread outwards. After a few weeks the cycle was completed, leaving in most instances a relatively normal appearing skin. Approximately 20 per cent of the Rongelap group developed lesions which were more se vere. These lesions might be considered as comparable to second degree thermal burns. The deeper lesions occurred principally on the feet and (a a lesser extent on the scarp and qeck and in one case on the ear, Blister formation was not common. However, on the feet, some large bullae (blisters) appeared. After a few days, the hyperpigmented lesions showed wet desquamiation with weeping and crusting, leaving depigmented raw surfaces of varying area. Someof these lesions became secondarily infected. Epithelium rapidly covered the ulcerated areas within a week to 10 days. Pigmentation followed during the next few weeks. As healing occurred many of the more severe lesions (particularly on the neck and antecubital fossae) developed a thickening of the skin with an “orange peel” appearance and a dusky, grayish-brown color (see Plate 3.4). 35 oe eee 8 ote ew 1 oe va . .