In addition there would be a few chromosomal defects and
recessive diseases and a few congenial defects due to a single
. gene defectg and chromosome aberrations.
TiptotalAncidencelatequitbri
n
s110 -to 27,000/ygare.
e The total incidence at equilibrium is 1100 to z1,{o00/year.
These
at equilibrium, the maximum would be 0.75% or 0.15% in. the first generation.
e
These are equivalent to 0.15% per rem at equilibrium and 0.03%/rem
in the first generation.
b.
Based on Overall Il] Health
Overall] il] health:
-
5% - 50% of i11 health is proportional to the
nufat ion rate using 20% and doubling dose of 20 rem, 5 rem per generation
_ would eventually lead to a 5% increase in il] health.
Thus the rate of overall il] health is 1%/rem at equilibrium or 0.2%/rem
in first generation.
For estimating the potential genetic derived health defects in the Bikini
wo
| population it was decided to use a risk coefficient of 0.2% per rem in the
i
i
first generation recognizing that it was probably very conservative.
\
S
B.—BEIR-IIT
ACAI
“Tr cancer (Table V-4)