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4:
4
nmA. .
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BEIR-I__
1.
Cancer (Tables 3-3 and 3-4)
Derived
Cancer deaths/year in U.S.
Cancer deaths/10° person rem
from 0.1 rem/year
) Ue
:
(pop = 197,863,000)
Absolute
Relative
Absolute
516
738
26
37
30 year
1210
2436
61
123
lifetime
elevated risk
1485
8340
75
42)
Leukemia
Relative
Other Cancers
elevated risk
Range
1726-2001
3174-9078
87-101
160-458
From the above the minimium estimate of cancer risk would be given by a
risk coefficient of 87/10 6 person rem and the maximum by 458/10° person
Thus, these two risk coefficients were used to define a range of
rem.
estimated cancer deaths.
———
2.
Genetic Effects (from Page 1 & 2 BEIR-I)
o
@.
Based on specific defects aS
gyren/30year reproductive generation would cause in the
(
first generation 100-1800 cases of dominant diseases and
defects per year (3.6 million births/year) or 5-times this
amount at equilibrium.
The 1800 cases represent an increase
of 0.05% incidences per year first generation and 0.25% at =
equilibrium.
al