Appendix V Findings of Epidemiological Studies of Cancer in Irradiated Populations (From J. Shapiro, Radiation Protection, pp. 260-4, Harvard U. Press, Cambridge, MA, 1972} NOt Cases Subject of study { Hiroshima and Nagasaki A-homb survivors (bomb exploded 1945} 2 Hiroshima and Nagasaki A-bomhbh survivors (women) Waneho et al., 1¥64 (238) Follow-up Dose Ne. of Form of in exposed Observed | «pected thine tyr) (Ror rads) persons? cancer group? exposed’ Leukemla Leukemta ci 6 1% | 20 5-13 Brill et al.. 1962 (813 3) Hiroshima and Nagasaki A-homb survivors exposed prenatally 40 Japanese A-bomb survivors exposed 13-21 IQ U-20) 21-80 85.070 13 184 if not *1-320 S695 Leukemia m4 20 O-4 [U-39 40-849 UU-LY9 200 2 O0KS 1.262 RS7 KO? Ka] Breast Breast Breast Breast Breast cancer cuncer cancer cancer Cancer 3 5 2 4 6 73 3 2 2 23 Unknown Unexposed _ ventral %40 2.45% Breast cancer Breast cancer , 2 23 & | bd S00 person-rads! 1.202 All cancers rorys ALP cancers, Q7s Jablon and Kate, 1870 (93) 17 within 1400 m of detonution (died P9S0-1962)) Angevine and Jablon gutopsies ti! Shs ‘ Os except deukemla 1964 (95) S Children exposed prenatally due to abdominal x-ray to mother fexposed 1945-19%6 and died hetore end of 1954). Court Brown et 2-12 & Children exposed prenatally (born 4-13 30 Lot Leukemia 77 goo All cancers af 1960 (239) 1.2 im fO47-) 984 and died before end of i960) MarMuhon, [92 6240) 7 intants whe recemed irradtulion of chest hefore age & mo oin tregtment tor enlarged thymus (treated KS 60 : 13-38 6) -600 1926-1957 follow-up inchas} Hempelmann et al. $46? (160) Lower dose group 2.207 Dhyrotd Thyra (benign) Leukemts 4 4 3 Qn xO 1 45 Phy rod !4 06 Phyronl (benign) 15 60 3 s° 0 t} 003 OSs (32.226 person Yr al riski! Higher dose xrotp 4OX (LEAS per Leukemig son yriuat risk) Mo Tatants irradiated routiaely wich X-Fays to anterior mediastinum It)-20 75-450) thostly, 140 14al, ing tud- through small (4 X doom) port. 7 ing 244 days after birth as “apparently harmless and perhaps benelicial procedure” («-ray 1938-46, follow-up 1956-58) Contiet ai. with en lurzed thymus DPhyroid carcinouna Leukemia 1960 (146) 4 Children treated with «-rays to head, neck, or chest for various benign conditions, mainly “enlurged”” thymus and adenitis, treated before age 16 and tallowed tillage 230 Saenger et ati asa) Children treated betore age 16 with x-rays tor enlarged (hymus, Upto 2s S80 (4) §0-200 036 0) 200-000 (F204 L.pd44 {hyroid Phyrot (henign! 3872 Leukemia tl ? 0 0 ul. 1960 (292) 1O) Not given Pertussis, and head and neck diseases. and died belore age 23 (treated 1930-1956, follow: up 1940-19S56@+ Murray et al 19849 (24)) - 134 - I4