re¥ eee UNCLASSIFIED Cc. Early effects of exposure to internal radiation D. What are the criteria for picking out the harmful radioelements included in fallout? 1. How sure are we that all the harmful ones have been picked out a. Strontium b. Cesium c. Rare earths d. Plutonium e. Iodine E. Delayed effects due either to single massive doses or to protracted chronic exposure; enumeration of effects of interest;: dose dependence 1. Examples 2. Relationships between the two types of dosings F, Mechanisms and responses of man to radiation and radioactivity 1. Briefly review chain of events a, Physical effects ‘b, Biochemical and chemical effects ce. Cellular effects ad. Effects of whole organism 2. Processes of physical interaction - physical effects a. Significance of alpha, beta, gamma rays, and neutrons in the process b. Significance of these rays with regard to penetration and whether introduced within the organism or arising from outside 3. Chemical and biochemical changes a, Direct effect of lonization on vital cell molecules b. Indirect effects as a result of lonization of water in the presence of oxygen ec. Relationship and importance ~17 -

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