so, “4 UNCLASSIFIED SPECIFIC QUESTIONS FOR DISCUSSION A, All low level effects are extrapolations from high level effects. How secure is this extrapolation? Discuss its relationship to the non-thresholg character of genetic effects, and to the question of threshold of bone cancer. -. Are there any distinctions between temporary and permanent (long term) damages, between repairable and irreparable damage? Are there special criteria for small groups of persons as compared with large populations with regard to radiation? Is there a difference between small and large populations? Between large populations and the whole population? Does the distinction apply only to genetic effects? Discuss the known effects of radiation on such aspects | of the human being as mental posture, personality, intelligence, other, etc. Are there any ¢hemical reinforements of body defenses againgt radiation? What about drugs recently annouyiced as being of possible use for X-ray dosages ?. What is to be gained or lost by the record-keeping recently proposed for each person covering his lifetime history of radiation dosage? q How much radiation and radioactivity was man naturally exposed to and medically exposed to before weapon firing began? Are the dosage standards for individuals and populations adequate for Sr90° What are the factors for genetics, skeleton age, age of individual, health of person, etc.? How adequate is the radium model as a basis for predicting Sr90 damage in man? K, What is the behavior of radioiodine in man from a damece gn dosage point of view? What about Csi ty cl » ete? Is the biological effect of Sr90 and its daughter y90 similar or the same as that of external radiation of any sort? XI. The Impact of the Present State of Affairs: Summary, Interrelationships, and Implications on Policy (oral, inserts, bibliography) A. In essence, what is the state of our knowledge in the areas discussed as relevant to the "fallout problem"; what do we know about: 1. The amount of radiation and radioactivity released by weapons fired to date - 21 - : i

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