2) Erythroblastosis A newborn baby with this condition was followed from birth until discharge from the hospital (2 weeks). received a transfusion. On the first day of life the baby Nevertheless the hematocrit fell rapidly and on the 10th day another transfusion was given. This was followed by a small rapid fall in hematocrit, then by a leveling-off at 35%. At this time the clinical condition was very good and the child was discharged. During the first week the red cell cholinesterase values were well below the normal (adult) range. On the first two days the plasma contained 3 to 4 times the amount of red cell type of cholinesterase found in normal (adult) plasma; this fell to a normal value on the seventh day. During the second week the red cell cholinesterase rose rapidly the titre increasing by 30% by the time the baby was able to maintain its own hematocrit level without transfusion. Reticulocytes at this time were 3%. Here again the red cell cholinesterase was an early-appearing and valuable criterion in evaluating the physiological state of the bone marrow, the need for further transfusion and the prognosis. 3) Carcinoma of the Head of the Pancreas Two cases have been studied. October. One was reported partially in Each had severe icterus and partially acholic stools, esterase values somewhat below the lower limit of normal. Each had cholin- This finding was re- garded as evidence against a hemolytic process and against a purely mechanical obstruction such as a stone in the common duct. It was thought more likely that a malignant process, (carcinoma or abdortinal Hodgkin's), was the causeof, the. ee clack. obstruction. In both cases lapargtony F ; ES entapeedtand hadsaclema et a, by auvhority of tae U.S. t the head of the pancreas. OP ? 4) Per Disappearance dPeRse cateroderinatetase Pati bielvSRY Blood