Table 18 Correlation of Immunoelectrophoretic and Peripheral Blood Findings With Age and Radiauon Exposure!) (D =decrease; I = increase) Unexposed group . Exposed group Change Correlation Percent dif. Significance Criterion with age with age (7 value) from unexposed (p value) Lymphocyte transformation D 0.89 - 1.1 0.68 Serum proteins Total serum proteins Albumen Total globulins I D I 35 45 38 — 15 + 15.0 —17.1 2+ O01 Oi I I I 43 32 75 — 20.0 ~ 6.0 — 18.3 Alpha-1 Alpha-2 Beta Gamma Immunoglobulins I A (IgA) I Lambdalight chains I D (IgD) M(IgM) G (IgG) Kappalight chains K/L ratio Blood findings Hematocrit Sedimentation rate 37 ~31.0 01 49 ~17.0 05 24 —14.0 15 I I I I 20 .20 78 96 I 41 D I + 0.4 .98 74. 22 69 74 + 2.9 +11.4 07 .08 91 .44 — 01 — 13.8 1 04 D 45 Platelets D 65 D I 30 4.0 8.0 3.0 37 72 Total leukocytes Lymphocvtes Neutrophils — — — — OL -03 01 —~ 25 — 84 9 04 Table 19 Serum Proteins, 1973-1974 Group Total protein Albumen Alpha 1 Alpha 2 Beta Gamma Total globulin Rongelap Ailingnae Utirik Unexposed 7.76+0.70 7.99+0.51 7.600.50 7.60+0.71 4.22+0.50 4.30+0.37 4.29+0.43 4.1140.45 0.20+0.05 0.19+0.07 0.16+0.06 0.19+0.06 0.69+0.12 0.72+0.15 0.69+0.30 0.75+0.14 1.08*+0.24 1.03+0.20 0.89+0.23 1.00+0.24 1.59+0.41 1.76+0.38 1.67+0.45 1.57+0.48 3.54+0.58 3.60+0.56 3.330.50 3.52 40.54 podiploid levels were related also to radiation; this was more pronouncedin the males, with the exposed having 2.8 times as many hypodiploid cells as the unexposed, whereas the exposed females had 1.3 times as manyas the unexposed. Polyploid levels were not found to be related to radiation. Both sex and chromosomesize appeared as factors possibly relatec to hypodiploid levels. In all subjects, regardless of sex or exposure, the largest and most frequent loss of chromosomes wasin the G(Y)group (2.3 times expectedloss). In the C(X) group, females lost 15.2% more chromosomes than expected and males 12.6% less. No sex or radiation effect was apparent in the otherfive chromosomegroups. A series of additional cultures indicated the presence of . : romosome breakage factor in the plasmaof the exposed subjects. In cultures of the latter, chromosome aberrations