52
with marked growth retardation (Nos. 3 and 35).
Ty levels before surgery were lower in subjects exposed in childhood than in unexposed controls.
Subjects exposed as adults who developedeither
benign or malignant thyroid lesions did not show
notable impairment of thyroid function. The
serum iodine levels of exposed and unexposed
people for the past 15 years are given in Appendix 8.
In 1965, the rates of urine and thyroid accumulation of 132T were measured over a 4-hr period in
21 Rongelap subjects, of whom 9 were unexposed
and 12 were exposed as adults.18 The data are
summarized in Table 26. Compared with North
American normal values obtained in 196318
(urine, Ag: =2; thyroid, Ag; =1; thyroid fraction
=0.33), both the exposed and unexposed Marshallese showed slow urine and thyroid transfer
rates of extrathyroid iodide but a high thyroid fraction. Similar studies done in 1972 on 12 Rongelapese without detectable thyroid abnormalities,
Table 28
Thyroid Status of Exposed Rongelap Subjects Without Recognized Thyroid Lesions, 1974
Subject No.
and sex
Age
(1974)
Plasma T,, pe/dl
Pre-TSH
24 hr post-TSH
Increment*
Plasma TSH,**
pU/ml
6.9
6.8
4.7
4.5
9.2
6.5
7.8
8.3
5.3
5.3
12.8
8.7
0.9
15
0.6
0.8
3.6
2.2
7.0
3.9
2.1
45
<b0
4.4
3.9
3.5
1.9
2.0
32
4.4
6.3
3.1
2.6
5.1
5.0
2.2
2.4
1.6
3.9
4.2
1.6
0.8
1.0
2.0
0.9
2.4
3.6
3.2
39
3.1
6.0
1.5
2.3
4.7
88
3.0
3.4
3.8
70
2.3
1.4
3.9
3.0
2.7
2.7
4.2
5.3
6.3
2.7
4M
6M
7M
9M
10M
12F
58
21
56
42
44:
38
24F
34 F
35 M
37 M
39 F
33
65
33
40
35
8.2
7.1
5.9
4.6
8.3
12.1
10.6
7.8
6.6
11.5
48 F
51 F
66 F
68 M
70 F
73M
76M
78 F
80 M
B81 F
82 M
83 M
85 M
1F
11M
14F
22 F
27M
44M
58 F
63 F
67 F
26
45
52
64
35
38
31
57
66
28
70
20
20
74
70
45
37
36
24
79
56
34
7.2
6.9
7.0
8.9
7.9
7.8
5.4
6.3
8.1
5.8
5.8
6.2
7.8
5.1
68
6.7
35
75
58
8.2
82
7.4
12.2
9.1
9.4
10.4
11.8
12.0
7.0
7.1
9.1
7.8
6.7
8.6
11.4
32M
47M
24
28
16M
41M
71F
Mean + S.D.
59
64
48
6.4
6.0
8.3
9.4
1.9
3.4
4.2
*Normalin 13 Pittsburgh subjects: 4.7 1.0 pg/dl.&
4.4
185
9.1
14.4
16.7
21.7
18.4
18.6
25.5
21.2
10.3
75
8.4
6.61.7
5.3
TBG-
binding capacity,
pg T,/dl
<1.0
7.0
2.35412
**Measured in pre-TSH samples. Normal is <5 pU/m!.