UNCLASSIFIED
higher than that received by the respiratory system. The integrated
dose received by the large intestine over the 28-day experimental period
was twice that received by the respiratory system, stomach or small
intestine.
The finding that the G.I, tract can serve as a portal of entry for sol-
uble fission-product aerosols following an inhalation exposure implies
that an evaluation of the internal hazard associated with an inhalation
exposure must take into account those parameters which influence transport across the G.J, membrane as well as the more commonly considered
factors which determine transport across the alveolar membrane,
Approved by:
et
POA.
ABEBEL be,oe
Captain (MC) USN
Acting Head, Biological and
Medical Sciences Division
For the Scientific Director
-20UNCLASSIFIED
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