Figure 63)£ p ryblems.”” We consider here the one-dimensional case he result jp which is expressed as follows [ Kea") fle’) da’ = gle) + ele) b |, but mog' upling light were f(z’) is the unknowndistribution of radioactivity he seintilla.! 2"x2' PILOT B tion in eff. since, ult}. Co®® coi. by the fact that the amounts of radioaetivity sought in the human body are unusually small. Hence, careful study must be devoted to the selection of response kernels of width most appropriate to optimize the amount of needed information. : equation, yields ap. Experimentally our experience was gained with a fili- form source (~0.7 mm width) consisting of a fine catheter ~200 cm long filled with uniform Cs!*’ microspheres of about 0.2 nCi and shaped as a sequence of sinusoidal waves of varying frequency and extending about 60 cm. The detector was either a 3” diameter Nal crystal with “ill-posed Av. Res. 432 ps three collimators or a cylindrical rod 2” diameter and Av. ps/em 142 i Average FWHM = 3.04cm BOT 20 {0 oO 10 ot 20 CMS OF ROD hic, 64—Proportionality between distance and transit time l T t REAL DISTRIBUTION FWHM = 8.5 cm oe FWHM=1i.0 cm -----FWHM =15.0 cm T TT ; 460 wo i; \ 50 ° RELATIVE AMOUNT OF ACTIVITY mM oO Tr 25 60 em long covered bylead bricks separated from spaces ranging from 1 to 5 em, as indicated in Figure 61. Theresults concerning W4,;,, namely the effect of the kernel width on the solution f(2"), are illustrated in Figure 65. As were all our results, they were obtained by the smoothing technique, described elsewhere“) and programmed in a 3600 computer. Our f(z’), the true distribution, is shown bythesolid line; our calculated solu- 4° 0 10 20 30 cm RELATIVE AMOUNT OF ACTIVITY listribution® lem of un n equation, appropriate Inanimate phantoms containing relatively intense sources. g(x) 1s the counting rate detected at the position x In practice, the physical problem is further complicated NANOSECONCS oarameten x’, We assumethat it can be determined very accurately for practical purposes by prolonged measurements over e(z) stands for the error whose limits are known from knowledgeof g(x), althoughits actual value is unknown. No detail can be given here of the methods of solving this equation for f(x’) once K (z,x’) and g(x) are given. lisplay sys. entifies thet unding thet counting rate registered by the scintillator at x due to the presence of an ‘ideal unit point source”situated at and is subject to both statistical and experimentalerror. with Al mylar reflector ater in any e detectior* thicknesse* dth of the! per unit length of the body. The kernel K(z,z’) is the 60 Fic. 65.—Influence of kernel resolution on detail of f(z’) MOK viet { bt