Provide subjecre with a one-liter or larger plastic botrle which has been pre-treated with thymol preservative. Note subjects name, location, date and time on sample bottle. Instruct subject to void and empty bladder just before beginning sample collection, and co wash hands before each successive voiding inco the sample concainer. Collece all urine for the nexe 24 hours in the sample concainer, including a final voiding to empty che bladder just before returning the container to the field-trip team or its representative. Note date and tine of final voiding. The same container may be used for single-void samples. Ask subject to wait until he or she has to urinate, wash hands, then void into concainer until bladder is empty. (2) Larzge-volume samoles Provide subjece with a 24 gallon or 5 gallon “cubitainer" or similar plastic container which has been pre-treated with thymol. Note subject's name, location, dace and rime on container. Instruct subject to void and empty bladder just before beginning sample collection, and to wash hands before each successive voiding into the sample container. Collect all urine for the next 120 hours (5 days) or longer if possible (maximum: 10 days). Just before returning the container to the fieldtrip team ac the end of the sampling period, the bladder should be empcied in one final voiding. Note the date and cime of the end of the sampling period on the container. D. Sample Container Preparation, and Post-Collection Treatment All sample containers should be "pre-treated" by adding 15 ml of 10% thymol solution in alcohol. The solution should be swirled in the conrainer to completely coat the sides, and the top should be left off until the alcohol evaporates leaving a dry chymol residue coacing its inner surfaces. After sample collection, 10 ml of concentrared HNO3 should be added to each container per liter of urine collected. Sample volume may be estimated The amount (volume) of HNO3 added and date should be noted on the sample container. The container may then be sealed and packed for shipmenc to BNL. Upon arrival at BNL, the sample volume and pH should be measured, and additional coneentrated HNO3 added to adjusce the pH to ~2.0. The samples may then be submitted for analysis.

Select target paragraph3