The accumuPatton of data from these surveysis Auingnae and Utrik groups were similar but less marked. Certain unexplained fluctuations have becoming increasingly voluminous. Since conditions have not been favorable for performance of occurred trom vear to vear in the peripheral blood computing procedures to store and manipulate the data, the annual surveyreports published bythis Labpratory are made as complete as possible. This biood elements as represented by mean population levels occurred as follows. extensive statistical analvses or use of electronic report, therefore, includes a considerable amount levels of the comparison populations as well as of the exposed groups. Depression af the peripheral Lymphocytes fell promptiv and bvthe third dav of raw data, much of it tn appendices. so that were about 55%c of the control values in adults. calculationsif desired. slight recoveryafter six months. At 2 vears, at- others mav have an opportunity to make further This report also contains a brief addendum on the vegetation of Rongelap Island. Summary of Past Findings Reports have been published on the findings of surveys made at the following.times after expo- sure: initial examination,' 6 months.: | vear,* 2 years,’ 3 years,> and @ years.* The following isa | brief summaryof the findings previously reported. During the first 24 to +8 hr after exposure, about % of the Rongelap people experienced anorexia @nd nausea. A few vomited andhad diarrhea. Many also experienced itching and burning of the skin, and a few complained oflachrymation and burning of the eyes. Followingthis, the people remained asymptomatic until about 2 weeks after the accident, when cutaneous lesions and loss of hair developed, due largely to beta ir- radiation of the skin. It was apparent when the people werefirst examined, a few days after expo- sure, that the lymphocytes were considerably depressed and that significant doses of radiation had probably been received, In addition to the whole- body dose of radiation and the beta irradiation of the skin, radiochemical analyses of the urine showed that measurable amounts of radioactive material had also been absorbed internally. The effects of the radiation can best be summarized under three headings according to the mode of ex- and slightly lower in children. There was only though further recovery was evident, the mean values of these cells.were still found to be below the comparison gopulatioggdevels (75 to 80%). At 3 years the mean lymphocydcounts wereslightly below those of the comparig@n population. At years the mean level appeared to be about the same as that of the com#ariseg population, but many gounts remained lower. Neutrophil levels fluctuated considerably dur- ing the first few weeks but fell gradually to a low of about 30% ef comparison population levels by the 6th wetafter exposure. Slow recover¥en- sued, but-at 6 monthsthey werestill slightly below the unexposed levels. However,dby | year post ex- posure they had returned to the level of the comparison population and have remained so, with the possible exception of those of children < 12 years old, which generally have been lower than those of the unexposed children of comparable age. Platelets fell to about 30% of the unexposed values by the 4th week. By 6 months they had reached 70% of the controls: at 1 year the mean platelet count was still below that of the control population but higher than at the 6-month survey. Although further increases were apparent at the 2-, 3-, and +-vear examinations, the levels were still below those of the comparison population. Changes in hematocrit were not remarkable in anv of the groups. Clinical examinations revealed no disease proc- The changes in the peripheral blood of the more heavily exposed Rongelap people who received esses or symptoms which could be attributed to radiation effects, aside from skin lesions, loss of hair, and early symptoms. Epidemics of chicken pox and measles occurred. The diseases encountered were no moresevere or frequent in the irradiated group than in the unexposed group, even during the period of greatest depression of periph- logical examinations(see Figures 33, 35, and 38, and Appendices | and 2}. The changes in the population died of disease: (1) a 46-vear-old man with a hypertensive heart disease which had been posure: penetrating irradiation, skin trradiation. and internal irradiation. . e PENETRATING IRRADIATION 175 r will be reviewed in the section on hemato- 1185552 eral blood elements. Three persons in the exposed

Select target paragraph3