-9to the body from this material is approximately 0.01 mr/day which is less than 5% of the radiation to the body from cosmic rays ard the radium in the soil. RADIATION EFFECTS IN MAN In the present discussion, it is obviously impossible to present in any detail the pathology of radiation injury. This extremely complex subject has been voluminously developed in the medicai literature and is generally available. The important radiation effects fall into two broad groups, one pertaining to the individual himself and the second related to questions of inheritance of the results of radiation damage to the germ celis. The first category we may call the somatic and the second the genetic effects. Somatic Effects: Here we must distinguish between the effects of external irradiation and those of internally ingested bomb residues. With respect to the immediate region of the explosion and to the areas of close-in radioactive fallout in the case of surface or near surface detonations let me say at once tnat the external radiation hazard is overwhelmingly the important one and the ingestion of radioactive bomb products in this region is relatively trivial in comparison with the external hazard. The effects of external radiation are not qualitatively greatly different for the various types of nuclear radiation but the regions and tissues of the body affected are very much dependent upon the physical characteristics and energies involved. Thus the highly energetic gamma and neutron radiations penetrate the entire body while the soft gamma rays and beta radiation have only limited penetration through the skin. Alpha radiation is of no external consequence because of its extremely limited penetration. The immediate effects of whole body gamma radiation are determined by the dosage received and the rate of delivery. The systems most fundamentally affected are the central nervous system, the blood forming organs and tissues and the gastrointestinal tract. The time of onset of symptoms may vary from a few minutes for extremely high doses delivered very rapidly to several weeks for smaller doses delivered more slowly. In general our previously published figures for 50% lethality at approximately 400 (more)

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